Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents：defining priorities to reduce cancer disparities in different geographic regions of the world[J]. J Clin Oncol, 2006, 24：2137-50. [2] Yamanaka S, Olaru AV, An F, et al. MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancer[J]. Dig Liver Dis, 2012, 44（7）：589-96. [3] Faltejskova P, Besse A, Sevcikova S, et al. Clinical correlations of miR-21 expression in colorectal cancer patients and effects of its inhibition on DLD1 colon cancer cells[J]. Int J Colorectal Dis, 2012, 27（11）：1401-1408. [4] Ma WJ, Lv GD, Tuersun A, et al. Role of microRNA-21 and effect on PTEN in Kazakh’s esophageal squamous cell carcinoma[J]. Mol Biol Rep, 2011, 38：3253-3260. [5] Zheng ST, Huo Q, Tuerxun A, et al. The expression and activation of ERK/MAPK pathway in human esophageal cancer cell line EC9706[J]. Mol Biol Rep, 2011, 38（2）：865-872. [6] Zhu Q, Wang Z, Hu Y, et al. miR-21 promotes migration and invasion by the miR-21-PDCD4- AP-1 feedback loop in human hepatocellular carcinoma[J]. Oncol Rep, 2012, 27（5）：1660-1668. [7] Gao W, Xu J, Liu L, et al. A systematic-analysis of predicted miR-21 targets identifies a signature for lung cancer[J]. Biomed Pharmacother, 2012, 66（1）：21-28. [8] Wong CK, Lau KM, Chan IH, et al. MicroRNA-21* regulates the prosurvival effect of GM-CSF on human eosinophils[J]. Immunobiology, 2013, 218（2）：255-262. [9] Ling M, Li Y, Xu Y, et al. Regulation of miRNA-21 by reactive oxygen species-activated ERK/NF-κB in arsenite-induced cell transformation[J]. Free Radic Biol Med, 2012, 52（9）：1508- 1518. [10] Liu LZ, Li C, Chen Q, et al. MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1α expression[J]. PLoS One, 2011, 6（4）：e19139.
