全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

抗菌肽作为饲料添加剂的研究进展

, PP. 43-48

Keywords: 抗菌肽,饲料添加剂,研究进展

Full-Text   Cite this paper   Add to My Lib

Abstract:

抗菌肽是生物体抵抗外界病原体侵袭而产生的一类小分子活性多肽,是生物体内先天性防御系统的重要组成部分。抗生素污染问题是目前影响我国畜牧与水产养殖业可持续健康发展的重大科技问题,由此引起的养殖产品中违禁抗生素残留成为制约我国出口创汇和食品安全的瓶颈,饲料中大量添加抗生素是导致抗生素超标的主要原因之一。寻找能够替代抗生素的环保型饲料添加剂,研制出无抗生素的环境友好型饲料,是我国畜牧与水产养殖业健康发展的迫切需求。就抗菌肽的来源,不同功能以及作为饲料添加剂在养殖中的应用作一简要综述。。

References

[1]  Seal BS, Lillehoj HS, Donovan DM, et al. Alternatives to antibiotics:a symposium on the challenges and solutions for animal production[C]//Animal health research reviews. Conference of Research Wor-kers in Animal Diseases, 2013:1-10.
[2]  Kaufmann BB, Hung DT. The fast track to multidrug resistance[J]. Molecular Cell, 2010, 37(3):297-298.
[3]  王兴顺, 耿艺介, 李文楚, 等. 抗菌肽抗菌机制及其应用研究进展[J]. 微生物学免疫学进展, 2012, 40(4):70-76.
[4]  Li Y, Qu H, Xiang Q, et al. Overview on the recent study of antimicrobial peptides:origins, functions, relative mechanisms and application[J]. Peptides, 2012, 37(2):207-215.
[5]  Pigeon C, Ilyin G, Courselaud B, et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload[J]. Journal of Biological Chemistry, 2001, 276(11):7811-7819.
[6]  Chen JY, Lin WJ, Lin TL. A fish antimicrobial peptide, tilapia hepcidin TH2-3, shows potent antitumor activity against human fibrosarcoma cells[J]. Peptides, 2009, 30(9):1636-1642.
[7]  Zasloff M. Antimicrobial peptides of multicellular organisms[J]. Nature, 2002, 415(6870):389-395.
[8]  Jenssen H, Hamill P, Hancock REW. Peptide antimicrobial agents[J]. Clin Microbiol Rev, 2006, 19(3):491-511.
[9]  Riley MA, Wertz JE. Bacteriocins:evolution, ecology, and applica-tion[J]. Ann Revi Microbiol, 2002, 56(1):117-137.
[10]  Hajji M, Jellouli K, Hmidet N, et al. A highly thermostable antimicrobial peptide from Aspergillus clavatus ES1:biochemical and molecular characterization[J]. Journal of Industrial Microbiology & Biotechnology, 2010, 37(8):805-813.
[11]  Stec B. Plant thionins-the structural perspective[J]. Cellular and Molecular Life Sciences CMLS, 2006, 63(12):1370-1385.
[12]  Wang KJ, Huang WS, Yang M, et al. A male-specific expression gene, encodes a novel anionic antimicrobial peptide, scygonadin, in Scylla serrata[J]. Mol Immunol, 2007, 44(8):1961-1968.
[13]  黄文树. 锯缘青蟹一种新的阴离子抗菌肽scygonadin 及其基因的分离与鉴定[D]. 厦门:厦门大学, 2006.
[14]  Huang WS, Wang KJ, Yang M, et al. Purification and part characterization of a novel antibacterial protein Scygonadin, isolated from the seminal plasma of mud crab, Scylla serrata(Forsk?l, 1775)[J]. J Exp Mar Biol and Ecology, 2006, 339(1):37-42.
[15]  范丹青. 拟穴青蟹(Scylla paramamosain)Histone 2A 的基因克隆, 表达及其合成肽 Sphistin 的抗菌特性与抗菌机理研究[D]. 厦门:厦门大学, 2011.
[16]  Wang KJ, Cai JJ, Cai L, et al. Cloning and expression of a hepcidin gene from a marine fish(Pseudosciaena crocea)and the antimicrobial activity of its synthetic peptide[J]. Peptides, 2009, 30(4):638-646.
[17]  王克坚, 周红铃, 杨明. 海水养殖鲈鱼分离出一种hepcidin 抗菌肽新基因[J]. 厦门大学学报:自然科学版, 2004, 43(3):286-287.
[18]  Ren HL, Wang KJ, Zhou HL, et al. Cloning and organisation analy-sis of a hepcidin-like gene and cDNA from Japan sea bass, Lateola-brax japonicus[J]. Fish Shellfish Immunol, 2006, 21:221-227.
[19]  陈君慧, 王克坚, 周红玲, 等. 花鲈肝脏 hepcidin 相关 cDNA Hepc2 的克隆及序列分析[J]. 中国生态农业学报, 2007, 15(3):129-132.
[20]  杨明, 王克坚, 周红玲. 我国海水养殖真鲷分离出 hepcidin 抗菌肽新基因[J]. 高技术通讯, 2004, 14:323-328.
[21]  杨明, 王克坚, 曲海东, 等. 真鲷鳃组织 cDNA 文库的构建与 hepcidin 抗菌肽基因序列的扩增[J]. 水产学报, 2006, 30(5):627-632.
[22]  Yang M, Wang KJ, Chen JH, et al. Genomic organization and tissue-specific expression analysis of hepcidin-like genes from black porgy(Acanthopagrus schlegelii)[J]. Fish & Shellfish Immunology, 2007, 23(5):1060-1071.
[23]  蔡晶晶, 杨明, 蔡灵, 等. 黑鲷抗菌肽 hepcidin 在毕赤酵母中的表达及其抗菌活性[J]. 厦门大学学报:自然科学版, 2009, 48(5):738-743.
[24]  Yang M, Chen B, Cai JJ, et al. Molecular characterization of hepcidin AS-hepc2 and AS-hepc6 in black porgy(Acanthopagrus schlegelii):expression pattern responded to bacterial challenge and in vitro antimicrobial activity[J]. Comp Biochem Physiol B:Biochem Mol Biol, 2011, 158(2):155-163.
[25]  Ganz T. Defensins:antimicrobial peptides of innate immunity[J]. Nat Rev Immunol, 2003, 3(9):710-720.
[26]  Zanetti M. Cathelicidins, multifunctional peptides of the innate immunity[J]. J Leukoc Biol, 2004, 75(1):39-48.
[27]  Zasloff M. Magainins, a class of antimicrobial peptides from Xenopus skin:isolation, characterization of two active forms, and partial cDNA sequence of a precursor[J]. Proceedings of the National Academy of Sciences, 1987, 84(15):5449-5453.
[28]  Steiner H, Hultmark D, Engstr?m ?, et al. Sequence and specificity of two antibacterial proteins involved in insect immunity[J]. Nature, 1981, 292:246-248.
[29]  Scudiero O, Galdiero S, Nigro E, et al. Chimeric beta-defensin analogs, including the novel 3NI analog, display salt-resistant antimicrobial activity and lack toxicity in human epithelial cell lines[J]. Antimicrob Agents Chemother, 2013, 57:1701-1708.
[30]  Landon C, Thouzeau C, Labbé H, et al. Solution structure of spheniscin, a β-defensin from the penguin stomach[J]. Journal of Biological Chemistry, 2004, 279(29):30433-30439.
[31]  Kuhn-Nentwig L, Müller J, Schaller J, et al. Cupiennin 1, a new family of highly basic antimicrobial peptides in the venom of the spider Cupiennius salei(Ctenidae)[J]. Journal of Biological Chemistry, 2002, 277(13):11208-11216.
[32]  Peng H, Yang M, Huang WS, et al. Soluble expression and purification of a crab antimicrobial peptide scygonadin in different expression plasmids and analysis of its antimicrobial activity[J]. Protein Expression and Purification, 2010, 70(1):109-115.
[33]  Yoe SM, Kang CS, Han SS, et al. Characterization and cDNA cloning of hinnavin II, a cecropin family antibacterial peptide from the cabbage butterfly, Artogeia rapae[J]. Comparative Biochem Physiol B:Biochem Mol Biol, 2006, 144(2):199-205.
[34]  Ye J, Zhao H, Wang H, et al. A defensin antimicrobial peptide from the venoms of Nasonia vitripennis[J]. Toxicon, 2010, 56(1):101-106.
[35]  Baek JH, Lee SH. Isolation and molecular cloning of venom peptides from Orancistrocerus drewseni(Hymenoptera:Eumenidae)[J]. Toxicon, 2010, 55(4):711-718.
[36]  Dang XL, Tian JH, Yang WY, et al. Bactrocerin-1:A novel inducible antimicrobial peptide from pupae of oriental fruit fly Bactrocera dorsalis Hendel[J]. Archives of Insect Biochemistry and Physiology, 2009, 71(3):117-129.
[37]  Danesi R, Senesi S, Wout JW, et al. Antimicrobial peptides:therapeutic potential for the treatment of Candida infections[J]. Expert Opinion on Investigational Drugs, 2002, 11(2):309-318.
[38]  Zhang K, Lu Q, Zhang Q, et al. Regulation of activities of NK cells and CD4 expression in T cells by human HNP-1, -2, and-3[J]. Biochem Biophys Res Commun, 2004, 323(2):437-444.
[39]  Salvatore M, García-Sastre A, Ruchala P, et al. β-defensin inhibits influenza virus replication by cell-mediated mechanism(s)[J]. Journal of Infectious Diseases, 2007, 196(6):835-843.
[40]  Ryan LK, Dai J, Yin Z, et al. Modulation of human beta-defensin-1(hbd-1)in plasmacytoid dendritic cells(pdc), monocytes, and epithelial cells by influenza virus, herpes simplex virus, and sendai virus and its possible role in innate immunity[J]. J Leukoc Biol, 2011, 90:343-356.
[41]  Peng H, Liu HP, Chen B, et al. Optimized production of scygonadin in Pichia pastoris and analysis of its antimicrobial and antiviral activities[J]. Protein Expr Purif, 2012, 82(1):37-44.
[42]  Huang CM, Chen HC, Zierdt CH. Magainin analogs effective against pathogenic protozoa[J]. Antimicrob Agents Chemother, 1990, 34(9):1824-1826.
[43]  McGwire BS, Olson CL, Tack BF, et al. Killing of African trypanos-omes by antimicrobial peptides[J]. J Infect Dis, 2003, 188:146-152.
[44]  Haines LR, Thomas JM, Jackson AM, et al. Killing of trypanosom-atid parasites by a modified bovine host defense peptide, BMAP-18[J]. PLoS Neglected Tropical Diseases, 2009, 3(2):e373.
[45]  Jenssen H, Hamill P, Hancock REW. Peptide antimicrobial agents[J]. Clinical Microbiology Reviews, 2006, 19(3):491-511.
[46]  Cai L, Cai JJ, Liu HP, et al. Recombinant medaka(Oryzias melas-tigmus)pro-hepcidin:multifunctional characterization[J]. Comp Biochem Physiol B Biochem Mol Biol, 2012, 161:140-147.
[47]  Gutsmann T, Hagge SO, Larrick JW, et al. Interaction of CAP18-derived peptides with membranes made from endotoxins or phospholipids[J]. Biophys J, 2001, 80(6):2935-2945.
[48]  Chen Y, Xu X, Hong S, et al. RGD-Tachyplesin inhibits tumor growth[J]. Cancer Research, 2001, 61(6):2434-2438.
[49]  Charp PA, Rice WG, Raynor RL, et al. Inhibition of protein kinase C by defensins, antibiotic peptides from human neutrophils[J]. Biochemical Pharmacology, 1988, 37(5):951-956.
[50]  Zhu QZ, Hu J, Mulay S, et al. Isolation and structure of corticostatin peptides from rabbit fetal and adult lung[J]. Proceedings of the National Academy of Sciences, 1988, 85(2):592-596.
[51]  陈香, 谯仕彦, 李波, 等. 添加天蚕素抗菌肽对断奶仔猪生长性能的影响[J]. 中国饲料, 2011(12):25-26.
[52]  Choi SC, Ingale SL, Kim JS, et al. Effects of dietary supplementation with an antimicrobial peptide-P5 on growth performance, nutrient retention, excreta and intestinal microflora and intestinal morphology of broilers[J]. Animal Feed Science and Technology, 2013, 185(1):78-84.
[53]  马倩, 赵衍铜, 柏明娜, 等. 抗菌肽对芦花鸡生产性能和血清生化指标的影响[J]. 饲料研究, 2012(3):27-29.
[54]  Wu S, Zhang F, Huang Z, et al. Effects of the antimicrobial peptide cecropin AD on performance and intestinal health in weaned piglets challenged with Escherichia coli[J]. Peptides, 2012, 35(2):225-230.
[55]  van der Marel M, Adamek M, Gonzalez SF, et al. Molecular cloning and expression of two β-defensin and two mucin genes in common carp(Cyprinus carpio)and their up-regulation after β-glucan feeding[J]. Fish Shellfish Immunol, 2012, 32(3):494-501.
[56]  陈红羽, 谯仕彦. 日粮中添加抗菌肽 cecropin AD 对肉鸡大肠杆菌攻毒条件下肠道菌群和白介素-6 水平变代研究[J]. 饲料与畜牧:新饲料, 2012(5):51-52.
[57]  马卫明, 佘锐萍, 胡艳欣, 等. 猪小肠抗菌肽对雏鸡的促生长作用及其机理初探[J]. 中国农业科学, 2006, 39:1723-1728.
[58]  黄自然, 黄国庆, 黄水彤. 新型饲料添加剂抗菌肽饲养肉鸡的效果[J]. 广东蚕业, 2006, 40(1):30-34.
[59]  王克坚. 海洋鱼类和青蟹抗菌肽 hepcidin 和 scygonadin 的研究[J]. 厦门大学学报:自然科学版, 2011, 50:418-424.
[60]  Habets MG, Brockhurst MA. Therapeutic antimicrobial peptides may compromise natural immunity[J]. Biol Lett, 2012, 8:416-418.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133