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家畜诱导性多能干细胞研究进展

, PP. 28-33

Keywords: 家畜育种学,诱导性多能干细胞,胚胎干细胞

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Abstract:

目前,家畜胚胎干细胞(Embryonicstemcells,ESCs)建系技术还不完善,很多大型家畜都未能建立ESCs系,这在很大程度上限制了家畜相关研究的开展。诱导性多能干细胞(Inducedpluripotentstemcells,iPSCs)技术的建立,为迅速、高效的获得家畜多潜能干细胞提供了新方法。家畜iPSCs的建立,将推动家畜发育生物学、异种器官移植、人类疾病模型建立、家畜品种改良等研究。综述了家畜iPSCs技术的最新进展,并探讨了家畜iPSCs的应用前景。

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