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miR-143在脂肪细胞分化和脂类代谢中的作用

, PP. 34-38

Keywords: 微小RNA,miR-143,靶基因,脂类代谢

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Abstract:

miR-143是内源性非编码的RNA,在细胞的分化、发育、增殖、脂肪代谢及疾病产生等许多生物学过程中具有重要作用。miR-143与脂类代谢密切相关,主要通过与靶基因的相互作用,影响脂肪的分化,甘油三酯的合成等。针对miR-143合成、预测的靶基因以及靶基因的调控机制方面进行综述,阐述miR-143在脂肪代谢中的作用,以便为相关疾病的诊断、治疗方面提供新思路。

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