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表皮生长因子对肠道功能调控的研究

DOI: 10.3969/j.issn.1006-267x.2014.03.002

Keywords: 表皮生长因子,肠道,信号通路,功能调控

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Abstract:

肠道健康决定了动物的整体机能和生产力水平,改善肠道结构与功能对动物健康生长具有重要意义。在畜牧生产中,诸多因素均能导致动物肠道功能损伤、生产力降低和抗病力减弱。表皮生长因子是促生长因子家族成员之一,具有许多生物学作用。表皮生长因子作为有丝分裂原,可刺激细胞分裂、增殖,增加上皮组织的DNA与蛋白质合成等,其独特作用是促进肠道组织生长、发育及损伤后修复,与动物肠道结构和功能密切相关。本文主要就表皮生长因子介导的信号通路、促进肠道发育、修复受损肠道组织、影响肠道各种酶活性以及提高营养物质消化吸收等方面内容进行论述。

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