NEWSHOLME P, BRENNAN L, RUBI B， et al. New insights into amino acid metabolism, beta-cell function and diabetes[J]. Clinical Science, 2005, 108:185-194.
[2]
BARBML A. The use of arginine in clinical practice[C]//CYNOBER L A. Amino acid metabolism and therapy in health and nutritional disease. New York: CRC Press, 1995:361-372.
[3]
CALDER P C, YAQOOB P. Amino acids and immune function [C]//CYNOBER L A. Metabolic and therapeutic aspects of amino acids in clinical nutrition. 2nd ed. Boca Raton, F. L.: CRC Press, 2004:305-320.
[4]
FIELD C J, JOHNSON I A N, PRATT V C. Glutamine and arginine: immunonutrients for improved health[J]. Medicine and Science in Sports and Exercise, 2000, 32:377-388.
[5]
FIELD C J, JOHNSON I R, SCHLEY P D. Nutrients and their role in host resistance to infection[J]. Journal of Leukocyte Biology, 2002, 71:16-32.
[6]
MIYAKE K. Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors[J]. Seminars in Immunology, 2007, 19:3-7.
[7]
KAWAI T, SHIZUO A. The roles of TLRs, RLRs and NLRs in pathogen recognition[J]. International Immunology, 2009, 21:1-15.
[8]
AKIRA S, UEMATSU S, TAKEUCHI O. Pathogen recognition and innate immunity[J]. Cell, 2006, 124:783-801.
KLEEBERGER S R, SEKHAR P M R, ZHANG L Y， et al. Toll-like receptor 4 mediates ozone-induced murine lung hyperpermeability via inducible nitric oxide synthase[J]. American Journal of Physiology Lung Cellular and Molecular Physiology, 2001, 280:326-333.
[11]
PFAFFL M W. A new mathematical model for relative quantification in real-time RT-PCR[J]. Nucleic Acids Reserch, 2001, 29:2002-2007.
[12]
陆成平.兽医微生物学[M].北京：中国农业出版社，2001.
[13]
SMITH K, OZINSKY A. Toll-like receptor-5 and the innate immune response to bacterial flagellin[J]. Current Topics in Microbiology and Immunology, 2002, 270:93-97.
[14]
MIZEL S B, ANNA N H, MARLENA A M， et al. Induction of macrophage nitric oxide production by gram-negative flagellin involves signaling via heteromeric Toll-like receptor 5/Toll-like receptor 4 complexes[J]. The Journal of Immunology, 2003, 170:6217-6223.
[15]
AUSMANN M, KIESSLING S, MESTERMANN S. et al. Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation[J]. Gastroenterology, 2002, 122:1987-2000.
[16]
VAN BEIJNUM J R, BUURMAN W A, GRIFFIOEN A W. Convergence and amplification of toll-like receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1)[J]. Angiogenesis, 2008, 11:91-99.
BLECHA F, CHARLEY B. Rationale for using immunopotentiators in domestic food animals[M]//Immunomodulation in domestic food animals. San Diego, C. A.: Academic Press, 1990:3-19.
[20]
KIM S W, WU G. Dietary arginine supplementation enhances the growth of milk fed young piglets[J]. Journal of Nutrition, 2004, 134:625-630.
[21]
WU G, KNABE D A, KIM S W. Arginine nutrition in neonatal piglets[J]. Journal of Nutrition, 2004, 134:2783-2790.
[22]
FRANK J W, ESCOBAR J, NGUYEN H V. et al. Oral N-carbamylglutamate supplementation increases protein synthesis in skeletal muscle of piglets[J]. Journal of Nutrition, 2007, 137:315-319.
[23]
WU G, FΜLLER W B, TERESA A D. et al. Important roles for the arginine family of amino acids in swine nutrition and production[J]. Livestock Science, 2007, 112:8-22.
[24]
LI P, YIN Y L, LI D, et al. Amino acids and immune function[J]. British Journal of Nutrition, 2007, 98:237-252.
[25]
POPOVI P J, ZEHLII H J, OCHOA J B. Arginine and immunity[J]. Journal of Nutrition, 2007, 137:1681-1686.
[26]
LIU Y L, JING J H, YONG Q H， et al. Dietary arginine supplementation alleviates intestinal mucosal disruption induced by Escherichia coli lipopolysaccharide in weaned pigs[J]. British Journal of Nutrition, 2008, 100:552-560.
RODRIGUEZ D, ALEXANDRE C K, ELIANA L F M, et al. Bacterial lipopolysaccharide signaling through Toll-like receptor 4 suppresses Asthma-like responses via nitric oxide synthase 2 activity[J]. The Journal of Immunology, 2003, 171:1001-1008.
[31]
FROST R A, GERALD J N, CHARLES H L. Lipopolysaccharide stimulates nitric oxide synthase-2 expression in murine skeletal muscle and C2C12 myoblasts via Toll-like receptor-4 and c-Jun NH2-terminal kinase pathways[J]. American Journal of Physiology Cell Physiology, 2004, 287:C1605-C1615.
