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瘤胃异常代谢产物脂多糖对奶牛血浆中代谢产物和激素的影响及其机制

DOI: 10.3969/j.issn.1006-267x.2012.03.007

Keywords: 瘤胃,内毒素,脂多糖,代谢,激素,奶牛

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Abstract:

当奶牛饲粮中精饲料水平提高时,瘤胃液pH下降,奶牛常会发生亚急性瘤胃酸中毒(SARA),瘤胃内产生大量异常代谢产物,其中主要是细菌内毒素脂多糖(LPS)。在SARA时期,外周血液中的LPS浓度升高,可导致奶牛发生一系列免疫应答,奶牛代谢也发生相应的变化。血浆葡萄糖、非酯化脂肪酸浓度升高,血浆氨基酸、β-羟丁酸、胆固醇和矿物质的浓度发生变化,血浆中的各种激素水平也会发生变化。这些代谢变化进而影响奶牛产奶量、乳脂和乳蛋白含量。本文对LPS对奶牛血浆代谢产物和激素水平的影响进行综述,并就其机制进行探讨。

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