全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

下丘脑对脂类的营养感应及其参与食欲调控的机制

DOI: 10.3969/j.issn.1006-267x.2013.07.001

Keywords: 下丘脑,脂肪酸,丙二酰辅酶A,脂肪酸转位酶,内源性大麻素

Full-Text   Cite this paper   Add to My Lib

Abstract:

食欲的形成与机体健康密切相关,并受控于营养信号、活性氧以及一系列激素信号的调节,下丘脑是各种食欲信号整合的主要中枢。最新研究表明,脂类营养物质可以被下丘脑特化的能量敏感神经元所感应,脂肪酸及其在细胞内的代谢产物分别以非代谢依赖性和代谢依赖性的方式参与机体能量稳态的调节,对于食欲调节以及能量平衡具有重要影响。本文综述了下丘脑对脂类的营养感应及其参与食欲调控的机制。

References

[1]  BRAINE A.Update on the duck market in 2011-2012[J].TeMA-Techniques et Marches Avicoles,2012(23):15-19.
[2]  LIU Y,XU X L,WANG X C,et al.Effect of different processes on taste compounds of duck meat[J].Food Science,2008,29(3):127-130.
[3]  LIU Y,XU X L,ZHOU G H.Comparative study of volatile compounds in traditional Chinese Nanjing marinated duck by different extraction techniques[J].International Journal of Food Science and Technology,2007,42(5):543-550.
[4]  DALEY C A,ABBOTT A,DOYLE P S,et al.A review of fatty acid profiles and antioxidant content in grass-fed and grain-fed beef[J].Nutrition Journal,2010,9(10):10-21.
[5]  李建军,文杰,陈继兰.禽肉风味的影响因素[J].国外畜牧科技,2002,29(1):27-29.
[6]  POTOKAR M C,SKRLEP M.Factors in pig production that impact the quality of dry-cured ham:a review[J].Animal,2012,6(2):327-338.
[7]  张晶晶,王锡昌,刘源,等.共轭亚油酸对樱桃谷鸭肉挥发性风味成分的影响[J].江苏农业学报,2010,26(5):1064-1069.
[8]  姚勇芳.肉类风味及其影响因素[J].肉类工业,2001(1):40-41.
[9]  GRAHAM S F,KENNEDY T,CHEVALLIER O,et al.The application of NMR to study changes in polar metabolite concentrations in beef longissimus dorsi stored for different periods post mortem[J].Metabolomics,2010,6(3):395-404.
[10]  SONCIN S,CHIESA L M,CANTONI C,et al.Preliminary study of the volatile fraction in the raw meat of pork,duck and goose[J].Journal of Food Composition and Analysis,2007,20(5):436-439.
[11]  杨烨,冯玉兰,李忠荣,等.性别和营养水平对福建河田鸡风味前体物质含量的影响[J].畜牧兽医学报,2006,37(3):242-249.
[12]  MOTTRAM D S.Flavour formation in meat and meat products:a review[J].Food Chemistry,1998,62(4):415-424.
[13]  MADRUGA M S,ELMORE J S,ORUNA CONCHA M J,et al.Determination of some water-soluble aroma precursors in goat meat and their enrolment on flavour profile of goat meat[J].Food Chemistry,2010,123(2):513-520.
[14]  YE M H,CHEN J L,ZHAO G P,et al.Correlation between polymorphisms in ADSL and GARS-AIRS-GART genes with inosine 5''-monophosphate (IMP) contents in Beijing-you chickens[J].British Poultry Science,2010,51(5):609-613.
[15]  刘哲,吴建平.羊肉风味的影响因素及研究现状[J].中国畜牧兽医,2005,32(1):28-30.
[16]  KOLA B,FARKAS I,CHRIST-CRAIN M,et al.The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system[J].PLoS One,2008,3(3):e1797.
[17]  ELMORE J S,MOTTRAM D S.The role of lipid in the flavour of cooked beef[J].Developments in Food Science,2006,43:375-378.
[18]  YANG S B,TIEN A C,BODDUPALLI G,et al.Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons[J].Neuron,2012,75:425-436.
[19]  POCAI A,LAM TONY K T,GUTIERREZ-JUAREZ R,et al.Hypothalamic KATP channels control hepatic glucose production[J].Nature,2005,434:1026-1031.
[20]  ANDERSSON U,FILIPSSON K,ABBOTT C R,et al.AMP-activated protein kinase plays a role in the control of food intake[J].Journal of Biological Chemistry,2004,279(13):12005-12008.
[21]  MINOKOSHI Y,KIM Y B,PERONI O D,et al.Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase[J].Nature,2002,415:339-343.
[22]  MOUNTJOY P D,BAILEY S J,RUTTER G A.Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity[J].Diabetologia,2007,50(1):168-177.
[23]  KOHNO D,SONE H,MINOKOSHI Y,et al.Ghrelin raises Ca2+ (i) via AMPK in hypothalamic arcuate nucleus NPY neurons[J].Biochemical and Biophysical Research Communications,2008,366(2):388-392.
[24]  李建军,文杰,陈继兰,等.品种和日龄对鸡肉滋味呈味物及香味前体物含量的影响[J].畜牧兽医学报,2003,34(6):548-553.
[25]  BAUCHART C,REMOND D,CHAMBON C,et al.Small peptides (<5 kDa) found in ready-to-eat beef meat[J].Meat Science,2006,74(4):658-666.
[26]  KOUTSIDIS G,ELMORE J S,ORUNA CONCHA M J,et al.Water-soluble precursors of beef flavour:Ⅰ.Effect of diet and breed[J].Meat Science,2008,79(1):124-130.
[27]  HOCQUETTE J F,GONDRET F,BAEZA E,et al.Intramuscular fat content in meat-producing animals:development,genetic and nutritional control,and identification of putative markers[J].Animal,2010,4(2):303-319.
[28]  刘源,徐幸莲,王锡昌,等.脂肪对鸭肉风味作用研究[J].中国食品学报,2009,9(1):95-99.
[29]  COBOS A,VEIGA A,DIAZ O.Chemical and fatty acid composition of meat and liver of wild ducks (Anas platyrhynchos)[J].Food Chemistry,2000,68(1):77-79.
[30]  江新业,宋焕禄.部分家禽肉肌内脂肪及脂肪酸含量的测定与分析[J].无锡轻工大学学报,2004,23(5):26-28.
[31]  KOJIMA M,KANGAWA K.Ghrelin:from gene to physiological function[M]//REHFELD J F,BUNDGAARD H R.Cellular peptide hormone synthesis and secretory pathways.New York:Springer-Verlag Berlin Heidelberg,2010:185-205.
[32]  VARELA L,VAZQUEZ M J,CORDIDO F,et al.Ghrelin and lipid metabolism:key partners in energy balance[J].Journal of Molecular Endocrinology,2011,46(2):43-63.
[33]  KOLA B,KORBONITS M.Shedding light on the intricate puzzle of ghrelin’s effects on appetite regulation[J].Journal of Endocrinology,2009,202(2):191-198.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133