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磷脂酰肌醇3-激酶/丝苏氨酸蛋白激酶信号途径及其在肌肉生长发育中的调控机制

DOI: 10.3969/j.issn.1006-267x.2013.04.004

Keywords: 磷脂酰肌醇3-激酶,丝苏氨酸蛋白激酶,信号途径,细胞凋亡,肌肉生长发育

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Abstract:

磷脂酰肌醇3-激酶/丝苏氨酸蛋白激酶(PI3K/Akt)是一类特异性催化磷脂酰肌醇(PI)的激酶,其信号途径是细胞内重要的信号转导通路之一,广泛参与动物机体的新陈代谢过程。本文就PI3K/Akt信号途径的结构、活化机制及其在细胞凋亡和肌肉生长发育中的调控机制进行综述。

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