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半胱胺盐酸盐和LHRH-A对黄鳍鲷生长激素分泌的影响

, PP. 147-153

Keywords: 半胱胺盐酸盐,促黄体素释放激素类似物,黄鳍鲷,生长激素

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Abstract:

研究了生长抑素抑制剂半胱胺盐酸盐(CSH)和促黄体素释放激素类似物(LHRH-A)对黄鳍鲷生长激素(GH)分泌的影响.黄鳍鲷垂体GH含量在单独注射不同剂量CSH(25,50,100μg/gb.w)后2h均显著提高,注射后24h恢复正常.黄鳍鲷血清中GH水平在注射CSH(100μg/gb.w)后2h和CSH(25,50μg/gb.w)后6h均明显提高.单独注射LHRH-A(0.1μg/gb.w)后2h黄鳍鲷垂体GH含量和血清中GH水平均明显提高.注射CSH和LHRH-A后6h垂体GH含量明显高于单独注射CSH或LHRH-A,而血清GH水平在注射后12h明显高于单独注射CSH或LHRH-A.结果表明CSH和LHRH-A都能明显刺激黄鳍鲷垂体合成和释放GH,并且与CSH作用存在剂量依存关系,CSH和LHRH-A联合注射比单独注射作用更明显,作用的时间更持久.

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