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大黄鱼溶藻弧菌病组织中巨噬细胞移动抑制因子的检测及意义

DOI: 10.3969/j.issn.0253-4193.2014.08.012, PP. 111-116

Keywords: 大黄鱼,巨噬细胞移动抑制因子,溶藻弧菌,免疫组织化学

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Abstract:

本文应用免疫组织化学方法，对健康大黄鱼和患溶藻弧菌病大黄鱼组织中巨噬细胞移动抑制因子（macrophagemigrationinhibitoryfactor，MIF）蛋白进行了检测，以研究溶藻弧菌病大黄鱼组织中MIF的表达情况及其对预后的影响。结果表明，MIF在健康大黄鱼头肾、脾、肠各组织中均无表达；MIF在溶藻弧菌病大黄鱼各组织中高表达，表达强度从弱到强依次是肠、脾、头肾，MIF表达阳性率分别为：56%、64%、92%。推测MIF在大黄鱼溶藻弧菌病发病中发挥重要作用。

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