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用近红外光谱对组织氧测量方法的研究

Keywords: 近红外光谱多层生物组织氧无损监测技术饱和度Lambert-Beer定律集成光学器件人体组织学

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Abstract:

在多层生物组织模型下,提出了一种利用近红外光谱技术定量无损检测组织氧饱和度的方法,讨论了受试者具有不同的外层组织时,如何采用适当的校准方法使半定量测量组织血氧浓度变化值具有可靠性和可比性;自行设计的监测系统,结构较为简洁,其探头包括光源和2个检测器,光源采用双波长LED,检测器为集成光学器件,2个检测器分别放置在与光源不同距离的位置上;以240mmHg压力进行人体前臂组断,氧合血红蛋白HbO2、还原血红蛋白Hb的浓度变化和组织氧饱和度tSO2的测试结果与时间分辨光谱TRS方法所得结果一致;系统基线平稳,具有较好的稳定性和检测精度。

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