全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

生物组织脱水过程的太赫兹时域光谱

Keywords: 太赫兹,生物组织,脱水,吸收系数,折射率

Full-Text   Cite this paper   Add to My Lib

Abstract:

利用透射式太赫兹时域光谱(THz-TDS)技术对猪脂肪、肌肉和皮肤三种新鲜组织的持续脱水过程进行在线连续扫描,观察太赫兹波时域谱在组织脱水过程的变化,并分析比较三种组织脱水前后的太赫兹波吸收系数及折射率的改变及差异.结果表明,太赫兹波对新鲜组织含水量的改变十分敏感,新鲜组织的含水量是影响太赫兹波吸收系数的主要因素.同时,不同组织对太赫兹的吸收有明显差异,表明太赫兹光谱技术可以鉴别不同的组织类型.本研究为太赫兹技术在生物医学领域的进一步研究和应用提供了帮助.

References

[1]  1He M X, Chen T, Yang J L, et al. The application of terahertz imaging in tumor diagnosis[J].Tumor. (何明霞,陈涛,杨吉龙,等. 太赫兹成像技术在肿瘤诊断方面的应用. 肿瘤) 2012(12): 10391042.)
[2]  2Wallace V P, Fitzgerald A J, Pickwell E, et al. Terahertz pulsed spectroscopy of human Basal cell carcinoma[J]. Appl Spectrosc. 2006,60(10): 11271133.
[3]  3Fitzgerald A J, Wallace V P, Jimenez-Linan M, et al. Terahertz pulsed imaging of human breast tumors[J]. Radiology. 2006,239(2): 533540.
[4]  4Chiu C M, Chen H W, Huang Y R, et al. All-terahertz fiber-scanning near-field microscopy[J]. Opt Lett. 2009,34(7): 10841086.
[5]  5Wahaia F, Valusis G, Bernardo L M, et al. Detection of colon cancer by terahertz techniques[J]. Journal of Molecular Structure. 2011,1006(1): 7782.
[6]  6Joseph C S, Yaroslavsky A N, Neel V A, et al. Continuous wave terahertz transmission imaging of nonmelanoma skin cancers[J]. Lasers in Surgery and Medicine. 2011,43(6): 457462.
[7]  7Hassan A M, Hufnagle D C, El-Shenawee M, et al. Terahertz imaging for margin assessment of breast cancer tumors[C]. Microwave Symposium Digest (MTT), 2012 IEEE MTT-S International. IEEE, 2012: 13.
[8]  8Bruehlmeier M, Roelcke U, Bl A Uenstein P, et al. Measurement of the extracellular space in brain tumors using 76Br-bromide and PET[J]. Journal of Nuclear Medicine. 2003,44(8): 12101218.
[9]  9Pickwell E, Cole B E, Fitzgerald A J, et al. Simulation of terahertz pulse propagation in biological systems[J]. Applied physics letters. 2004,84(12): 21902192.
[10]  10Suen J Y, Tewari P, Taylor Z D, et al. Towards medical terahertz sensing of skin hydration[J]. Stud Health Technol Inform. 2009,142: 364368.
[11]  11Kindt J T, Schmuttenmaer C A. Far-infrared dielectric properties of polar liquids probed by femtosecond terahertz pulse spectroscopy[J]. The Journal of Physical Chemistry. 1996,100(24): 1037310379.
[12]  12Stanley H E, Buldyrev S V, Canpolat M, et al. The puzzle of liquid water: a very complex fluid[J]. Physica D: Nonlinear Phenomena. 1999,133(1): 453462.
[13]  13Starr F W, Nielsen J K, Stanley H E. Hydrogen-bond dynamics for the extended simple point-charge model of water[J]. Physical Review E. 2000,62(1): 579.
[14]  14Yada H, Nagai M, Tanaka K. Origin of the fast relaxation component of water and heavy water revealed by terahertz time-domain attenuated total reflection spectroscopy[J]. Chemical Physics Letters. 2008,464(4): 166170.
[15]  15Wang Y, Minamide H, Tang M, et al. Study of water concentration measurement in thin tissues with terahertz-wave parametric source[J]. Optics Express. 2010,18(15): 1550415512.
[16]  16Wang Y Y, Notake T, Tang M, et al. Terahertz-wave water concentration and distribution measurement in thin biotissue based on a novel sample preparation[J]. Physics in medicine and biology. 2011,56(14): 4517.
[17]  17Zhang Z, Yu X, Zhao H, et al. Component analysis to isomer mixture with THz-TDS[J]. Optics communications. 2007,277(2): 273276.
[18]  18Duvillaret L, Garet F, Coutaz J L. A reliable method for extraction of material parameters in terahertz time-domain spectroscopy[J]. Selected Topics in Quantum Electronics, IEEE Journal of. 1996,2(3): 739746.
[19]  19Hoshina H, Hayashi A, Miyoshi N, et al. Terahertz pulsed imaging of frozen biological tissues[J]. Applied Physics Letters. 2009,94(12): 123901.
[20]  20Liu C, Cui E, Liu W, et al. Analysis on the characteristics of biological tissues based on the terahertz time domain spectroscopy system[C]. International Symposium on Photoelectronic Detection and Imaging 2011. International Society for Optics and Photonics, 2011: 81951M81951M7.
[21]  21Sun Y, Fischer B M, Pickwell-Macpherson E. Effects of formalin fixing on the terahertz properties of biological tissues[J]. Journal of biomedical optics. 2009,14(6): 64017.
[22]  22Ebbinghaus S, Kim S J, Heyden M, et al. An extended dynamical hydration shell around proteins[J]. Proceedings of the National Academy of Sciences. 2007,104(52): 2074920752.
[23]  23Singh R S, Taylor Z D, Culjat M O, et al. Towards THz medical imaging; reflective imaging of animal tissues[J]. Stud Health Technol Inform. 2008,132: 472474.
[24]  24Ashworth P C, Pickwell-Macpherson E, Provenzano E, et al. Terahertz pulsed spectroscopy of freshly excised human breast cancer[J]. Opt Express. 2009,17(15): 1244412454.
[25]  25He M, Azad A K, Ye S, et al. Far-infrared signature of animal tissues characterized by terahertz time-domain spectroscopy[J]. Optics Communications. 2006,259(1): 389392.
[26]  26Wilmink G J, Ibey B L, Tongue T, et al. Development of a compact terahertz time-domain spectrometer for the measurement of the optical properties of biological tissues[J]. Journal of Biomedical Optics. 2011,16: 47006.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133