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类猪圆环病毒因子P1VP2蛋白二级结构与B细胞表位预测

DOI: 10.7668/hbnxb.2009.05.010, PP. 45-49

Keywords: P1,二级结构,B细胞表位,生物信息学,预测

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Abstract:

旨为预测类猪圆环病毒因子P1VP2蛋白的B细胞表位。采用生物信息软件和互联网服务器,预测VP2的二级结构,分析VP2表面特性(亲水性、可塑性、可及性和抗原性),综合预测VP2的B细胞抗原表位。结果表明,P1VP2蛋白肽链的6-18和80-92区段为预测的B细胞表位优势区。多参数方案综合预测P1VP2蛋白的B细胞抗原表位,为进一步鉴定表位及设计疫苗奠定了基础。

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