Crowther J R,Reckziegel P O,Prado J A.Quantification of whole virus particles(146S)of Foot-and-mouth disease Virus in the presence of virus subunits(12S),using monoclonal an-tibodies in a sandwich ELISA[J].Vaccine,1995,13:1064-1075.
[3]
Duchesne M,Guerche J,Leqrand B,et al.The use of highly concentrated purified(by a large scale method)and long term liquid nitrogen stored foot-and-mouth disease viruses for the preparation of vaccines:physico-chemical quality controls and potency tests after storage[J].Dev Biol Stand,1981,50:249-259.
[4]
Doel T R,Collen T.Qualitative assessment of 146S particles of foot-and-mouth disease virus in preparations destined for vaccines[J].J Biol Standard,1982,10:69-81.
[5]
Reed L J,Muench H.A simple method of estimating fifty percentend points[J].Am J Hyg,1938,27:493-497.
[6]
Pay T W F,Hingley P L.Correlation of 140S antigen dose with the serum neutralizing antibody response and the level of protection induced in cattle by foot-and-mouth disease vaccines[J].Vaccine,1987,5:60-64.
Cartwright B,Chapman W G,Brown F.Serological and im-manological relationships between the 146S and 12S particles of Foot-and-mouth disease virus[J].J Gen Virol,1980,50:369-375.
[10]
Cowan K M.Antibody response to viral antigens[J].Adv Im-munol,1973,17:195-255.
[11]
Doel T R,Chong W K T.Comparative immunogenicity of 146S,75S and 12S particles of Foot-and-mouth disease Virus[J].Archives of Virology,1982,73:185-191.
[12]
Black L,Nicholls M J,Rweyemamu M M,et al.Foot-and-nlouth disease vaccination:a multifactofial study of the influ-ence of antigen dose and potentially competitive immunogens on the response of cattle of different ages[J].Res Vet Sci,1986,40(3):303-7.
[13]
Pay T W,Hingley P J.Foot and mouth disease vaccine po-tency tests in cattle:the interrelationship of antigen dose,serum neutralizing antibody response and protection from challenge[J].Vaccine,1993,11(3):392.
Bachrach H L.The determination of the sedimentation con-stant of a homogeneous component having the characteristics of the foot-and-mouth disease virus[J].Amer J Vet Res,1952,13:13-16.