Karahuseyinoglu S, Cinar O, Kilic E,et al. Biology of stem cells in human umbilical cord stroma:In situ and in vitro surveys [J]. Stem Cells, 2007,25 : 319 - 331.
[2]
Lumelsky N, Blondel O, Laeng P, et al. Differentiation of embryonic stem cells to insulin-secreting structures simi- lar to pancreatic islets [J]. Science, 2001,292 ( 5520 ) : 1389 - 1394.
[3]
Vaca P, Mart n F, Vegara-Meseguer J M, et al. Induction of differentiation of embryonic stem cells into insulin-se- creting ceils by fetal soluble factors [J]. Stem Cells, 2006,24 ( 2 ) : 258 - 265.
[4]
Segev H, Fishman B, Ziskind A, et al. Differentiation of human embryonic stem cells into insulin-producing clus- ters[J]. Stem Cells,2004,22(3 ) :265 - 274.
[5]
Moriscot C, Fraipont F D, Richard M J,et al. Human bone marrow mesenchymal stem cells can express insulin and key transcription factors of the endocrine pancreas devel- opmental pathway upon genetic and/or microenvironmen- tal manipulation in vitro [J]. Stem Cells, 2005,23 ( 4 ) : 594 - 603.
[6]
Seaberg R M,Smukler S R,Kieffer T J,et al. Clonal iden- tification of muhipotent precursors from adult mouse pan- creas that generate neural and pancreatic lineages [J]. Nat Biotech,2004,22 : 1115 - 1124.
[7]
Tai M H,Karl O L,Burra V M,et al. Characterization of gap junctional intercellular communication in immortalized human pancreatic ductal epithelial cells with stem cell characteristics [J]. Pancreas, 2003,26 ( 1 ) : 18 - 26.
[8]
Linning, Katrina D, Tai M H, et al. Redox-mediated en- richment of self-renewing adult human pancreatic cells that possess endocrine differentiation [J]. Potential Pan- creas,2004,29(3 ) :64 - 67.
[9]
Yang L J, Li S W, Hatch H, et al. In vitro transdifferenti- ation of adult hepatic stem cells into pancreatic endo- crine hormone-producing cells [J]. Proc Natl Acad Sci USA,2002,99:8078 - 8083.
[10]
Hori Y C, Gu X Y, Xie X D, et al. Differentiation of in- sulin-producing cells from human neural progenitor ceils [J]. PLoS Med,2005,2:347 -356.
[11]
Ende N,Chen R F, Reddi Alluru S. Effect of human um- bilical cord blood cells on glycemia and insulitis in type 1 diabetic mice [J]. Biochem Biophys Res Commun, 2004,325:665 - 669.
[12]
Ende N, Chen R F, Reddi A S. Transplantation of human umbilical cord blood cells improves glycemia and glo- merular hypertrophy in type 2 diabetic mice [J]. Bio- chem Biophys. Res Commun,2004,321:168 - 171.
[13]
Petsa A, Gargani S, Felesakis A,et al. Effectiveness of protocol for the isolation of Wharton''s Jelly stem cells in large-scale applications[J]. In Vitro Cell Dev Biol -Ani- mal,2009,45:573 - 576.
[14]
Chao K C,Chao K F,Fu Y S,et al. Islet-like clusters de- rived from mesenchymal stem cells in Wharton''s Jelly of the human umbilical cord for transplantation to control type 1 diabetes[J]. PLoS One,2008 (1) :1451.
[15]
Takahash I T, Kalka C, Masuda H,et al. Ischemia and cytokine induced mobiliazatio of bone marrow derived endothelial progeitor cells for neovasculation [J]. Nat Med, 1999,8:434 -438.
[16]
Karahuseyinoglu S, Kocaefe C, Balci D, et al. Functional structure of adipocytes differentiated from human umbili- cal cord stroma-derived stern cells[J]. Stern Cells,2008, 26(3) :682 -691.
[17]
Zulewski H,Abraham E J,Gerlach M J,et al. Multipo- tential nestin-positive stem cells isolated from adult pan- creatic endocrine, exocrine and hepatic phenotypes [J]. Diabetes,2001,50:521 - 533.
[18]
Otonkoski T,Beattie G M,Mally M I,et al. Nicotinamide is a potent inducer of endocrine differentiation in cul- tured human fetal pancreatic cells [J]. J Clin Invest, 1993.92 : 1459 - 1466.
[19]
Roche E,Buteau J,Aniento I,et al. Induction by glucose of genes coding for glycolytic enzymes in a pancreatic beta-cell line(INS-1 ) [J]. J Boil Chem,1997,272(5) : 3091 - 3098.
[20]
Ramiya V K, Maraist M, Arfors E,et al. Reversal of insu- lin dependent diabetes using islets generated in vitro from pancreatic stem ceils [J]. Nat Med, 2000,6 ( 3 ) : 278 - 282.
