Boch J,Scholze H,Schornack S,et al.Breaking the code of DNA binding specificity of TAL-type III effectors[J].Science,2009,326(5959):1509-1512.
[2]
Zhang F,Cong L,Lodato S,et al.Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription[J].Nature Biotechnology,2011,29(2):149-153.
[3]
Sanjana N E,Cong L,Zhou Y,et al.A transcription activator-like effector toolbox for genome engineering[J].Nature Protocols,2012,7(1):171-192.
[4]
Horvath P,Barrangou R.CRISPR/Cas,the immune system of bacteria and archaea[J].Science,2010,327(5962):167-170.
[5]
Barrangou R,Fremaux C,Deveau H,et al.CRISPR provides acquired resistance against viruses in prokaryotes[J].Science,2007,315(5819):1709-1712.
[6]
Lillest？l R K,Redder P,Garrett R A,et al.A putative viral defence mechanism in archaeal cells[J].Archaea,2006,2(1):59-72.
[7]
Lintner N G,Kerou M,Brumfield S K,et al.Structural and functional characterization of an archaeal clustered regularly interspaced short palindromic repeat(CRISPR)-associated complex for antiviral defense(CASCADE)[J].The Journal of Biological Chemistry,2011,286(24):21643-21656.
[8]
Deveau H,Barrangou R,Garneau J E,et al.Phage response to CRISPR-Encoded resistance in Streptococcus thermophiles [J].Journal of Bacteriology,2008,190(4):1390-1400.
[9]
Lillest？l R K,Shah S A,Brügger K,et al.CRISPR families of the crenarchaeal genus Sulfolobus:bidirectional transcription and dynamic properties[J].Molecular Microbiology,2009,72(1):259-272.
[10]
Westra E R,Swarts D C,Staals R H,et al.The CRISPRs,they are a-changin'':how prokaryotes generate adaptive immunity[J].Annual Review of Genetics,2012,46:311-339.
[11]
Marraffini L A,Sontheimer E J.Self versus non-self discrimination during CRISPR RNA-directed immunity[J].Nature,2010,463(7280):568-571.
[12]
Sorek R,Kunin V,Hugenholtz P.CRISPR-a widespread system that provides acquired resistance against phages in bacteria and archaea[J].Nature Reviews Microbiology,2008,6(3):181-186.
[13]
Dicarlo J E,Norville J E,Mali P,et al.Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems[J].Nucleic Acids Research,2013,41(7):4336-4343.
[14]
Hwang W Y,Fu Y,Reyon D,et al.Efficient genome editing in zebrafish using a CRISPR-Cas system[J].Nature Biotechnology,2013,31(3):227-229.
[15]
Bassett A R,Tibbit C,Ponting C P,et al.Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system[J].Cell Reports,2013,4(1):220-228.
[16]
Mali P,Yang L H,Esvelt K M,et al.RNA-Guided human genome engineering via Cas9[J].Science,2013,339(6121):823-826.
[17]
Miao J,Guo D,Zhang J,et al.Targeted mutagenesis in rice using CRISPR-Cas system[J].Cell Research,2013,23(10):1233-1236.
[18]
Li T,Huang S,Jiang W Z,et al.Hybrid proteins composed of TAL effectors and Fok I DNA-cleavage domain[J].Nucleic Acids Research,2011,39(1):359-372.
[19]
Moscou M J,Bogdanove A J.A simple cipher governs DNA recognition by TAL effectors[J].Science,2009,326(5959):1501.
[20]
Tesson L,Usal C,Ménoret S,et al.Knockout rats generated by embryo microinjection of TALENs[J].Nature Biotechnology,2011,29(8):695-696.
[21]
Lei Y,Guo X,Liu Y,et al.Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases(TALENs)[J].Proceedings of the National Academy of Sciences of the United States of America,2012,109(43):17484-17489.
[22]
Huang P,Xiao A,Zhou M,et al.Heritable gene targeting in zebrafish using customized TALENs[J].Nature Biotechnology,2011,29(8):699-700.
[23]
Mahfouz M M,Li L,Piatek M,et al.Targeted transcriptional repression using a chimeric TALE-SRDX repressor protein[J].Plant Molecular Biology,2012,78(3):311-321.
[24]
Li T,Liu B,Spalding M H,et al.High-efficiency TALEN-based gene editing produces disease-resistant rice[J].Nature Biotechnology,2012,30(5):390-392.
[25]
Liu J,Li C,Yu Z,et al.Efficient and specific modifications of the Drosophila genome by means of an easy TALEN strategy[J].Journal of Genetics and Genomics,2012,39(5):209-215.
[26]
Wood A J,Lo T W,Zeitler B,et al.Targeted genome editing across species using ZFNs and TALENs[J].Science,2011,333(640):307.
[27]
Li T,Huang S,Zhao X,et al.Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes[J].Nucleic Acids Research,2011,39(14):6315-6325.
Boch J,Bonas U.Xanthomonas AvrBs3 family-type III effectors:discovery and function[J].Annu Review Phytopathology,2010,48:419-436.
[30]
Deng D,Yan C,Pan X,et al.Structural basis for sequence-specific recognition of DNA by TAL effectors[J].Science,2012,335(669):720-723.
[31]
Kim Y G,Cha J,Chandrasegaran S.Hybrid restriction enzymes:Zinc finger fusions to Fok I cleavage domain[J].Proceedings of the National Academy of Sciences of the United States of America,1996,93(3):1156-1160.
[32]
Urnov F D,Rebar E J,Holmes M C,et al.Genome editing with engineered Zinc finger nucleases[J].Nature Reviews Genetics,2010,11(9):636-646.
[33]
Reyon D,Tsai S Q,Khayter C,et al.FLASH assembly of TALENs for high-throughput genome editing[J].Nature Biotechnology,2012,30(5):460-465.
[34]
Mahfouz M M,Li L,Shamimuzzaman M,et al.De novo-engineered transcription activator-like effector(TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks[J].Proceedings of the National Academy of Sciences of the United States of America,2011,108(6):2623-2628.
[35]
Grissa I,Vergnaud G,Pourcel C.The CRISPRdb database and tools to display CRISPRs and to generate dictionaries of spacers and repeats[J].BMC Bioinformatics,2007,8:172.
