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阔褶水蛙皮肤组织抗菌肽latouchiin-1和latouchiin-2的基因克隆和序列分析

DOI: 10.7668/hbnxb.2010.02.003, PP. 12-17

Keywords: 阔褶水蛙,抗菌肽,分子克隆,皮肤组织

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Abstract:

为了从生物体中寻找新颖的抗菌肽类药物分子,以阔褶水蛙(Hylaranalatouchii)为研究材料,运用3′RACE技术成功从其皮肤组织中筛选出2个抗菌肽前体cDNA编码序列,经blast生物信息学分析,确定其为首次发现,推导出的这2条新颖的抗菌肽序列,命名为latouchiin-1和latouchiin-2。

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