全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

群体感应系统的合成生物学研究进展

DOI: 10.11830/ISSN.1000-5013.2013.02.0165

Keywords: 合成生物学, 群体感应系统, 细胞浓度控制, 生物被膜信号通路

Full-Text   Cite this paper   Add to My Lib

Abstract:

群体感应系统通过释放到环境中的信号分子来进行交流,进而协调群体行为,因其结构简单、机理清晰而广泛应用于合成生物学的研究.简要介绍合成生物学的概念,着重阐述基于群体感应系统的合成生物学研究及其在细胞浓度控制、生物被膜信号通路和生物化工领域的应用.最后,探讨群体感应系统研究的不足,并做进一步展望.

References

[1]  王兆守,彭江海,胡译丹,等.合成生物学的工业应用[J].中国科学:化学,2011,41(4):709-716.
[2]  罗巅辉,余劲聪,方柏山.合成生物学的研究方向与应用[J].华侨大学学报:自然科学版,2009,30(1):1-5.
[3]  SMOLKE C D,SILVER P A.Informing biological design by integration of systems and synthetic biology[J].Cell,2011,144(6):855-859.
[4]  AHMAD S K,JAMES J C.Synthetic biology: Applications come of age[J].Nature Reviews Genetics,2010,11(2):367-379.
[5]  GIBSON D G,GLASS J L,LARTIGUE C,et al.Creation of a bacterial cell controlled by a chemically synthesized genome[J].Science,2010,329(5987):52-56.
[6]  MCDANIEL R,WEISS R.Advances in synthetic biology: On the path from prototypes[J].Current Opinion in Biotechnology,2005,16(4):476-483.
[7]  STAHLER P,BEIER M,GAO X,et al.Another side of genomics: Synthetic biology as a means for the exploitation of whole-genome sequence information[J].Journal of Biotechnology,2006,124(1):206-212.
[8]  Royal Society of Chemistry,Science and Technology Department.A third industrial revolution[J].Integrative Biology,2009,1:148-149.
[9]  熊燕,陈大明,赵国屏,等.合成生物学发展现状与前景[J].生命科学,2011,23(9):826-836.
[10]  RUBY E G,NEALSON K H.Symbiotic association of Photobacterium fischeri with the marine luminous fish Monocentris japonica: A model of symbiosis based on bacterial studies[J].The Biological Bulletin,1976,151(3):574-586.
[11]  MILLER M B,BASSLER B L.Quorum sensing in bacteria[J].Annual Review of Microbiology,2001,55(9):165-199.
[12]  FUQUA C,PARSEK M R,GREENBERG E.Regulation of gene expression by cell-to-cell communication: Acyl-homoserine lactone quorum sensing[J].Annual Review of Genetics,2001,35(12):439-468.
[13]  KARIG D K,SIUTI P,RETTERER S T,et al.Model for biological communication in a nanofabricated cell-mimic driven by stochastic resonance[J].Nano Communication Networks,2011,2(1):39-49.
[14]  DECINE J H,SHADEL G S,BALDWIN T.Identification of the operator of the Lux regulon from the Vibrio fischeri strain ATCC7744[J].Proceedings of the National Academy of Sciences of the United States of America,1989,86(15):5688-5692.
[15]  SAYUT D J.Engineering of artificial cellular circuits based on the LuxI-LuxR quorum-sensing system[D].Amherst:University of Massachusetts,2010.
[16]  YOU L C,COX R S,WEISS R,et al.Programmed population control by cell-cell communication and regulated killing[J].Nature,2004,428(6985):868-871.
[17]  BALAGADDE F K,SONG H,OZAKI J,et al.A synthetic Escherichia coli predator-prey ecosystem[J].Molecular Systems Biology,2008,4(187):1-8.
[18]  彭江海.人工群体感应通路的合成生物学研究[D].厦门:厦门大学,2011:15-44.
[19]  庄园,余劲聪,方柏山.酶定向进化技术及其在化学品生物转化中的应用[J].化学工程与装备,2009,6(3):89-91.
[20]  胡译丹.细胞浓度控制元件的合成生物学研究[D].厦门:厦门大学,2012:20-35.
[21]  WILLIAMS P,CAMARA M.Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: A tale of regulatory networks and multifunctional signal molecules[J].Current Opinion in Microbiology,2009,12(2):182-191.
[22]  PESCI E C,PEARSON J P,SEED P C,et al.Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa[J].Journal of Bacteriology,1997,179(10):3127-3132.
[23]  BRENNER K,KARIG D K,WEISS R,et al.Engineered bidirectional communication mediates a consensus in a microbial biofilm consortium[J].Proceedings of the National Academy of Sciences of the United States of America,2007,104(44):17300-17304.
[24]  HONG S H,HEDGE M,KIM J,et al.Synthetic quorum-sensing circuit to control consortial biofilm formation and dispersal in a microfluidic device[J].Nature Communications,2012,613(3):1616-1620.
[25]  ATSUMI S,HANAI T,LIAO J C.Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels[J].Nature,2008,451(2007):86-90.
[26]  ATSUMI S,HIGASHIDE W,LIAO J C.Direct photosynthetic recycling of carbon dioxide to isobutyraldehyde[J].Nature Biotechnology,2009,27:1177-1180.
[27]  SONDEREGGER M,SCHUMPERLI M,SAUER U.Metabolic engineering of a phosphoketolase pathway for pentose catabolism in Saccharomyces cerevisiae[J].Applied and Environmental Microbiology,2004,70(5):2892-2897.
[28]  TRINH C T,UNREAN P,SRIENC F.Minimal Escherichia coli cell for the most efficient production of ethanol from hexoses and pentoses[J].Applied and Environmental Microbiology,2008,74(12):3634-3643.
[29]  SCHIRMERR A,RUDE M A,GEORGE C,et al.Microbial biosynthesis of alkanes[J].Science,2010,329(5991):559-562.
[30]  ZHANG Y,EVANS B R MIELENZ J R,et al.High-yield hydrogen production from starch and water by a synthetic enzymatic pathway[J].Plos One,2007(5):1-6.
[31]  TAGUCHI S,YAMADA M,MATSUMOTO K,et al.A microbial factory for lactate-based polyesters using a lactatepolymerizing enzyme[J].Proceedings of the National Academy of Sciences of the United States of America,2008,105(45):17323-17327.
[32]  陈国强.我国“合成生物学”急需研究的问题[J].生物工程学报,2012,28(1):116-118.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133