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同位素  2014 

邻苯二甲酸二甲酯-D6的合成

DOI: 10.7538/tws.2014.27.02.0072, PP. 72-76

Keywords: 稳定同位素标记,邻苯二甲酸二甲酯,合成,功能材料

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Abstract:

以甲醇-D4和苯酐为原料,在缩合剂的催化下合成邻苯二甲酸二甲酯-D6,以消耗的甲醇-D4计算,邻苯二甲酸二甲酯-D6收率为88.0%。产品结构经质谱和核磁共振波谱等表征确定为目标化合物,氘原子同位素丰度为99.1%,纯度为99.0%,结果表明,合成方法操作简便,不会造成丰度稀释。合成的邻苯二甲酸二甲酯-D6可作为食品安全领域检测用同位素内标试剂。

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