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同位素  2000 

多巴胺转运蛋白显像剂β-CIT的合成及其碘标记

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Keywords: 多巴胺转运蛋白显像剂,β-CIT,合成,碘标记

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Abstract:

报道了β-CIT(2β-甲酯基-3β-(4’-碘苯基)托烷)及标记前体(2β-甲酯基-3β-(4’-(三丁基锡)苯基)托烷)的合成路线,化合物IR、NMR、MS、元素分析等数据与结构相符,由标记前体制备125/131I-β-CIT,标记率和放化纯度均>90%。

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