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同位素  2002 

~(117)Sn~m(Ⅳ)-EDTMP在体外骨模型上的吸附——Ⅰ.在羟基磷灰石上的吸附

, PP. 77-77

Keywords: (117)~Sn_m-EDTMP,羟基磷灰石(HA),吸附,解吸

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Abstract:

研究了~(117)Sn~m(Ⅳ)及~(117)Sn~m(Ⅳ)-EDTMP在体外骨模型羟基磷灰石(HA)上的吸附及解吸特性,探讨了其骨吸附机理。吸附研究表明~(117)Sn~m(Ⅳ)及~(117)Sn(Ⅳ)-EDTMP在HA上都有明显的吸附,其对~(117)Sn~m(Ⅳ)的吸附量大于对~(117)Sn~m(Ⅳ)-EDTMP的吸附量;pH对吸附有明显影响,酸性条件最有利于吸附,弱碱性条件最不利于吸附;温度对吸附几乎没有影响。解吸研究表明生理盐水和EDTMP对~(117)Sn~m(Ⅳ)-EDTMP的解吸量大于对~(117)Sn~m(Ⅳ)的解吸量。~(117)Sn~m(Ⅳ)-EDTMP的吸附机理研究初步表明当吸附量小于60μmol/g时,络合物以整个配位络合物吸附为主;当吸附量大于60μmol/g时,配位络合物整体吸附与~(117)Sn~m(Ⅳ)从配体到HA的转移络合同时存在。

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