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同位素  2004 

低剂量~(103)Pd支架抑制TIPSS分流道狭窄初探

, PP. 47-47

Keywords: 103Pd支架,放射治疗,TIPSS,狭窄

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Abstract:

探讨103Pd支架预防经静脉肝内门腔静脉内支架分流术(TIPSS)分流道狭窄的效果。健康乳猪18只行TIPSS,术后分为两组,分别置入103Pd支架和普通支架。并于术后4周、8周行血管造影、病理解剖和光镜管腔面积检测。门静脉造影显示4周时放射组2例、对照组3例狭窄;8周时放射组全部闭塞,对照组部分狭窄。术后4周肝实质段支架内径组织增生厚度(12.95MBq组)为3.64±1.01mm,对照组增生厚度为2.24±1.02mm,两组差异明显(P<0.05)。由此表明,9.25和12.95MBq103Pd支架均未能抑制TIPSS分流道术后狭窄。

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