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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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受体介导乳糖化重组人生长激素的肝靶向性
, PP. 197-197
Keywords: 乳糖基重组人生长激素(L-rhGH),肝靶向性,受体介导特性
Abstract:
研究了乳糖基重组人生长激素(L-rhGH)的肝靶向性。以131I标记L-rhGH和rhGH,然后进行家兔、鸡显像和家兔竞争结合实验;并用125I标记的L-rhGH和rhGH进行小鼠体内分布实验。结果表明L-rhGH具明显的肝靶向性,家兔最大肝摄取率达76.8%,是rhGH的2倍以上;与肝脏的结合具有ASGP-R受体介导特性。
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