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同位素  2004 

肺部恶性肿瘤组织摄取~(99)Tc~m-MIBI与Pgp表达的相关性

, PP. 157-157

Keywords: 肺恶性肿瘤,γ探测仪,99Tcm-MIBI,P-糖蛋白

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Abstract:

用99Tcm-MIBI术中γ探测法探讨活体肺部恶性肿瘤组织对99Tcm-MIBI的摄取和肿瘤细胞P-糖蛋白(Pgp)表达间的关系。结果表明,T/NT≤2的肺部恶性肿瘤组织Pgp含量明显高于T/NT>2的肺部恶性肿瘤组织;Pgp含量多寡与病理类型无关;肺部恶性肿瘤组织对99Tcm-MIBI的摄取与Pgp表达呈明显负相关,即肿瘤细胞高度表达Pgp时,99Tcm-MIBI摄取较低。

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