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手性联萘酚催化辛炔与苯甲醛的不对称加成反应研究

, PP. 536-539

Keywords: 不对称合成,手性联萘酚,辛炔,炔丙醇

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Abstract:

手性炔丙醇是合成许多天然产物和药物的重要中间体.报道了手性联萘酚催化辛炔与苯甲醛的不对称炔基锌加成反应,在室温下产物产率为91%,对映体过量为53%,为脂肪炔丙醇的对映选择性合成提供了一个新的方法

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