BBENTLEY K W.The Isoquinoline alkaloids[M]. Amsterdam: Harwood academic publishers, 1998
[2]
DAI G, LAROCK R C.Synthesis of 3-substituted 4-aroylisoquinolines via Pd-catalyzed carbonylative cyclization of o-(1-alkynyl)benzaldimines[J].Org Lett,2002,4(2):193-196
[3]
HUANG Q H, LAROCK R C.Synthesis of 4-(1-Alkenyl)isoquinolines by Palladium(II)-catalyzedcyclization/olefina
[4]
tion[J].J Org Chem, 2003, 68(3): 980-988
[5]
MMARTINE C D, ALAIN C, DANIELE C, et al.Diphenyl quinolines and isoquinolines: synthesis and primary biological evaluation[J].Bioorg Med Chem,2000,8(11):2629-2641
[6]
KONNO T, CHAE J, MIYABE T, et al.Regioselective one-step synthesis of 4-fluoro-alkylatedisoquinolines via carbopalladation reaction of fluorine-containing alkynes[J].J Org Chem,2005,70(24):10172-10174
[7]
YYANG Y Y, SHOU W G, CHEN Z B, et al.A tandem approach to isoquinolines from 2-azido-3-arylacrylates and α-diazocarbonyl compounds[J].J Org Chem,2008,73(10):3928-3930
[8]
FLORENTINO L, AZNAER F, VALDES C.Synthesis of polysubstituted isoquinolines through cross-coupling reactions with r-alkoxytosylhydrazones[J].Org Lett,2012,14(9):2323-2325
[9]
PPANDY G, BALAKRISHNAN M.Suzuki cross-coupling/reductive debenzyloxycarbonylation sequence for the syntheses of [c]annulated isoquinolines: application for the syntheses of pancratistatin-like isoquinolines[J].J Org Chem,2008,73(20):8128-8131
[10]
YANG D Q, BURUGUPALLI S, DANIEL D, et al.Microwave-assisted one-pot synthesis of isoquinolines, furopyridines, and thienopyridines by Palladium-catalyzed sequential coupling imination annulation of 2-bromoarylaldehydes with terminal acetylenes and ammonium acetate[J].J Org Chem,2012,77(9):4466-4472
[11]
IISHIKAWA T, SHIMOOKA K, NARIOKA T, et al.Anomalous substituent effects in the Bischler?Napieralski reaction of 2-aryl aromatic formamides[J].J Org Chem,2000,65(26):9143-9151
[12]
SSOTOMAYOR N, DOMINGUEZ E.Bischler?Napieralski cyclization?N/C-alkylation sequences for the construction of isoquinoline alkaloidsSynthesis of protoberberines and penzo[c]phenanthridines via C-2’-functionalized 3-arylisoquinolines[J].. J Org Chem,1996,61(12):4062-4072
[13]
YYOUN S W.Development of the Pictet?Spengler reaction catalyzed by AuCl3/AgOTf[J].J Org Chem,2006,71(6):2521-2523
[14]
GAO K, WU J.Synthesis of functionalized 1,2-dihydroisoquinolines via multicomponent one-pot reaction of 2-alkynylbenzaldehyde, amine, zinc, and allylic bromide or benzyl bromide[J].J Org Chem,2007,72(22):8611-8613
[15]
TOO P C, WANG Y F, CHIBA S.Rhodium(III)-catalyzed synthesis of isoquinolines from aryl ketone o-acyloxime derivatives and internal alkynes[J].Org Lett,2010,12(24):5688-5691
[16]
WANG B, LU B, JIANG Y W, et al.Assembly of isoquinolines via CuI-catalyzed coupling of β-keto esters and 2-halobenzylamines[J].Org Lett,2008,10(13):2761-2763
[17]
YU X X, WU J.Synthesis of functionalized isoquinolines via sequential cyclization/cross-coupling reactions[J].J Comb Chem,2009,11(5):895-899
[18]
TOO P C, CHUA S H, WONG S H, et al.Synthesis of azaheterocycles from aryl ketone o-acetyl oximes and internal alkynes by Cu - Rh bimetallic relay catalysts[J].J Org Chem,2011,76(15):6159-6168
[19]
DING Q P, WU J.Lewis acid- and organocatalyst-cocatalyzed multicomponent reactions of 2-alkynylbenzaldehydes, amines, and ketones[J].Org Lett,2007,9(24):4959-4962
[20]
WEI X H, ZHAO M, DU Z Y, et al.Synthesis of 1-aminoisoquinolines via Rh(III)-catalyzed oxidative coupling[J].Org Lett,2011,13(17):4636-4639
[21]
NIU Y N, YAN Y Z, GAO G L, et al.Synthesis of isoquinoline derivatives via Ag-catalyzed cyclization of 2-alkynyl benzyl azides[J].J Org Chem,2009,74(7):2893-2896
[22]
ZHENG L Y, JU J, BIN Y H, et al.Synthesis of isoquinolines and heterocycle-fused pyridines via three-component cascade reaction of arylk etones, hydroxylamine, and alkynes[J].J Org Chem,2012,77(13):5794-5800
[23]
YU X X, WU J.Synthesis of 1-(1H-indol-3-yl)-1,2-dihydroisoquinolines via AgOTf-catalyzed three component reactions of 2-alkynylbenzaldehydes, amines, and indoles[J].J Comb Chem,2010,12(2):238-244
[24]
KISHOR P, JEGANMOHAN M.Highly regio- and stereoselective ruthenium(II)-catalyzed direct ortho-alkenylation of aromatic and heteroaromatic aldehydes with activated alkenes under open atmosphere[J].Org Lett,2012,14(4):1134-1137
[25]
KISHOR P, JEGANMOHAN M.Ruthenium-catalyzed ortho-alkenylation of aromatic ketones with alkenes by C–H bond activation[J].Org Lett,2011,13(23):6144-6147
[26]
CHINNAGOLLA R K, PIMPARKAR S, JEGANMOHAN M.Ruthenium-catalyzed highly regioselective cyclization of ketoximes with alkynes by C- H bond activation: a practical route to synthesize substituted isoquinolines[J].Org Lett,2012,14(12):3032-3035
[27]
REDDY M V R, RAO M R, RHODES D, et al.Lamellarin α 20-Sulfate, an inhibitor of HIV-1 integrase active against HIV-1 virus in cell culture[J].J Med Chem,1999,42(11):1901-1907
[28]
KORNHAA? C, LI J, ACKERANN L.Cationic Ruthenium catalysts for alkyne annulations with oximes by C?H/N?O functionalizations[J].J Org Chem,2012,77(20):9190-9198
[29]
AUBRY A, PAN X S, FISHER L M, et al.Mycobacterium tuberculosis DNA gyrase: interaction with quinolones and correlation with antimycobacterial drug activity[J].Antimicrob Agents Chemother,2004,48(4):1281-1288
[30]
BAILLY C.Lamellarins, from A to Z: A family of anticancer marine pyrrole alkaloids[J].Curr Med Chem,2004,4(4):363-378
[31]
KORIVI R P, CHENG C H.Highly efficient synthesis of isoquinolines via Nickel-catalyzed annulation of 2-iodobenzaldimines with alkynes: evidence for dual pathways of alkyne insertion[J].Org Lett,2005,7(23):5179-5182
[32]
CHEN Z Y, WU J.Efficient generation of biologically active H-pyrazolo[5,1- a]isoquinolines via multicomponent reaction[J].Org Lett,2010,12(21):4856-4859
[33]
OKAMOTO N, TAKEDA K, YANADA R.Platinum-catalyzed, one-pot tandem synthesis of indoles and isoquinolines via sequential rearrangement of amides and aminocyclization[J].J Org Chem,2010,75(22):7615-7625
[34]
ZHENG D Q, LI S Y, WU J.An unexpected silver triflate catalyzed reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate[J].Org Lett,2012,14(11):2655-2657
[35]
LIM S G, LEE J H, MOON C W, et al.Rh(I)-catalyzed direct ortho-alkenylation of aromatic ketimines with alkynes and its application to the synthesis of isoquinoline derivatives[J].Org Lett,2003,5(15):2759-2761
[36]
GUIMOND N, FAGNOU K.Isoquinoline synthesis via rhodium-catalyzed oxidative cross-coupling/cyclization of aryl aldimines and alkynes[J].J Am Chem Soc,2009,131(34):12050-12051
[37]
TOO P C, WANG Y F, CHIBA S.Rhodium(III)-catalyzed synthesis of isoquinolines from aryl ketone o-acyloxime derivatives and internal alkynes[J].Org Lett,2010,12(24):5688-5691
[38]
TOO P C, CHUA S H, WONG S H, et al.Synthesis of azaheterocycles from aryl ketone o-acetyl oximes and internal alkynes by Cu - Rh bimetallic relay catalysts[J].J Org Chem,2011,76(15):6159-6168
[39]
WEI X H, ZHAO M, DU Z Y, et al.Synthesis of 1-aminoisoquinolines via Rh(III)-catalyzed oxidative coupling[J].Org Lett,2011,13(17):4636-4639
[40]
ZHENG L Y, JU J, BIN Y H, et al.Synthesis of isoquinolines and heterocycle-fused pyridines via three-component cascade reaction of arylk etones, hydroxylamine, and alkynes[J].J Org Chem,2012,77(13):5794-5800
[41]
KISHOR P, JEGANMOHAN M.Highly regio- and stereoselective ruthenium(II)-catalyzed direct ortho-alkenylation of aromatic and heteroaromatic aldehydes with activated alkenes under open atmosphere[J].Org Lett,2012,14(4):1134-1137
[42]
KISHOR P, JEGANMOHAN M.Ruthenium-catalyzed ortho-alkenylation of aromatic ketones with alkenes by C–H bond activation[J].Org Lett,2011,13(23):6144-6147
[43]
CHINNAGOLLA R K, PIMPARKAR S, JEGANMOHAN M.Ruthenium-catalyzed highly regioselective cyclization of ketoximes with alkynes by C- H bond activation: a practical route to synthesize substituted isoquinolines[J].Org Lett,2012,14(12):3032-3035
[44]
KORNHAA? C, LI J, ACKERANN L.Cationic Ruthenium catalysts for alkyne annulations with oximes by C?H/N?O functionalizations[J].J Org Chem,2012,77(20):9190-9198
[45]
KORIVI R P, CHENG C H.Highly efficient synthesis of isoquinolines via Nickel-catalyzed annulation of 2-iodobenzaldimines with alkynes: evidence for dual pathways of alkyne insertion[J].Org Lett,2005,7(23):5179-5182
[46]
OKAMOTO N, TAKEDA K, YANADA R.Platinum-catalyzed, one-pot tandem synthesis of indoles and isoquinolines via sequential rearrangement of amides and aminocyclization[J].J Org Chem,2010,75(22):7615-7625
[47]
BBENTLEY K W.The Isoquinoline alkaloids[M]. Amsterdam: Harwood academic publishers, 1998
[48]
DAI G, LAROCK R C.Synthesis of 3-substituted 4-aroylisoquinolines via Pd-catalyzed carbonylative cyclization of o-(1-alkynyl)benzaldimines[J].Org Lett,2002,4(2):193-196
[49]
HUANG Q H, LAROCK R C.Synthesis of 4-(1-Alkenyl)isoquinolines by Palladium(II)-catalyzedcyclization/olefina
[50]
tion[J].J Org Chem, 2003, 68(3): 980-988
[51]
KONNO T, CHAE J, MIYABE T, et al.Regioselective one-step synthesis of 4-fluoro-alkylatedisoquinolines via carbopalladation reaction of fluorine-containing alkynes[J].J Org Chem,2005,70(24):10172-10174
[52]
FLORENTINO L, AZNAER F, VALDES C.Synthesis of polysubstituted isoquinolines through cross-coupling reactions with r-alkoxytosylhydrazones[J].Org Lett,2012,14(9):2323-2325
[53]
YANG D Q, BURUGUPALLI S, DANIEL D, et al.Microwave-assisted one-pot synthesis of isoquinolines, furopyridines, and thienopyridines by Palladium-catalyzed sequential coupling imination annulation of 2-bromoarylaldehydes with terminal acetylenes and ammonium acetate[J].J Org Chem,2012,77(9):4466-4472
[54]
GAO K, WU J.Synthesis of functionalized 1,2-dihydroisoquinolines via multicomponent one-pot reaction of 2-alkynylbenzaldehyde, amine, zinc, and allylic bromide or benzyl bromide[J].J Org Chem,2007,72(22):8611-8613
[55]
WANG B, LU B, JIANG Y W, et al.Assembly of isoquinolines via CuI-catalyzed coupling of β-keto esters and 2-halobenzylamines[J].Org Lett,2008,10(13):2761-2763
[56]
TOO P C, CHUA S H, WONG S H, et al.Synthesis of azaheterocycles from aryl ketone o-acetyl oximes and internal alkynes by Cu - Rh bimetallic relay catalysts[J].J Org Chem,2011,76(15):6159-6168
[57]
WEI X H, ZHAO M, DU Z Y, et al.Synthesis of 1-aminoisoquinolines via Rh(III)-catalyzed oxidative coupling[J].Org Lett,2011,13(17):4636-4639
[58]
ZHENG L Y, JU J, BIN Y H, et al.Synthesis of isoquinolines and heterocycle-fused pyridines via three-component cascade reaction of arylk etones, hydroxylamine, and alkynes[J].J Org Chem,2012,77(13):5794-5800
[59]
KISHOR P, JEGANMOHAN M.Highly regio- and stereoselective ruthenium(II)-catalyzed direct ortho-alkenylation of aromatic and heteroaromatic aldehydes with activated alkenes under open atmosphere[J].Org Lett,2012,14(4):1134-1137
[60]
KISHOR P, JEGANMOHAN M.Ruthenium-catalyzed ortho-alkenylation of aromatic ketones with alkenes by C–H bond activation[J].Org Lett,2011,13(23):6144-6147
[61]
CHINNAGOLLA R K, PIMPARKAR S, JEGANMOHAN M.Ruthenium-catalyzed highly regioselective cyclization of ketoximes with alkynes by C- H bond activation: a practical route to synthesize substituted isoquinolines[J].Org Lett,2012,14(12):3032-3035
[62]
KORNHAA? C, LI J, ACKERANN L.Cationic Ruthenium catalysts for alkyne annulations with oximes by C?H/N?O functionalizations[J].J Org Chem,2012,77(20):9190-9198
[63]
KORIVI R P, CHENG C H.Highly efficient synthesis of isoquinolines via Nickel-catalyzed annulation of 2-iodobenzaldimines with alkynes: evidence for dual pathways of alkyne insertion[J].Org Lett,2005,7(23):5179-5182
[64]
OKAMOTO N, TAKEDA K, YANADA R.Platinum-catalyzed, one-pot tandem synthesis of indoles and isoquinolines via sequential rearrangement of amides and aminocyclization[J].J Org Chem,2010,75(22):7615-7625
[65]
BBENTLEY K W.The Isoquinoline alkaloids[M]. Amsterdam: Harwood academic publishers, 1998
[66]
MMARTINE C D, ALAIN C, DANIELE C, et al.Diphenyl quinolines and isoquinolines: synthesis and primary biological evaluation[J].Bioorg Med Chem,2000,8(11):2629-2641
[67]
YYANG Y Y, SHOU W G, CHEN Z B, et al.A tandem approach to isoquinolines from 2-azido-3-arylacrylates and α-diazocarbonyl compounds[J].J Org Chem,2008,73(10):3928-3930
[68]
PPANDY G, BALAKRISHNAN M.Suzuki cross-coupling/reductive debenzyloxycarbonylation sequence for the syntheses of [c]annulated isoquinolines: application for the syntheses of pancratistatin-like isoquinolines[J].J Org Chem,2008,73(20):8128-8131
[69]
IISHIKAWA T, SHIMOOKA K, NARIOKA T, et al.Anomalous substituent effects in the Bischler?Napieralski reaction of 2-aryl aromatic formamides[J].J Org Chem,2000,65(26):9143-9151
[70]
SSOTOMAYOR N, DOMINGUEZ E.Bischler?Napieralski cyclization?N/C-alkylation sequences for the construction of isoquinoline alkaloidsSynthesis of protoberberines and penzo[c]phenanthridines via C-2’-functionalized 3-arylisoquinolines[J].. J Org Chem,1996,61(12):4062-4072
[71]
YYOUN S W.Development of the Pictet?Spengler reaction catalyzed by AuCl3/AgOTf[J].J Org Chem,2006,71(6):2521-2523
[72]
CCHRZANOWSKA M, ROZWADOWSKA M D.Asymmetric synthesis of isoquinoline alkaloids[J].Chem Rev,2004,104(7):3341-3370
[73]
BBOUDOU M, EENDERS D.Asymmetric synthesis of tetrahydropalmatine via tandem 1,2-addition/cyclization[J].J Org Chem,2005,70(23):9486-9494
[74]
WALKER E R, LEUNG S Y, BARRETT A G M.Studies towards the total synthesis of Sch 56036; isoquinolinone synthesis and the synthesis of phenanthrenes[J].Tetrahedron Lett,2005,46(38):6537-6540
[75]
ROESCH K R, LAROCK R C.Synthesis of isoquinolines and pyridines via Palladium-catalyzed iminoannulation of internal acetylenes[J].J Org Chem,1998,63(1):5306-5307
[76]
GIRLING I R, WIDDOMSON D A.Cyclopalladated imines in synthesis 2: a new synthesis of isoquinolines[J].Tetrahedron Lett,1982,23(41):4281-4284
[77]
MAASSARANI F, PFEFFER M, LEBORGNE G.Control of the reactivity of cyclopalladated complexes for the synthesis of heterocyclic compounds[J].J Chem Soc Chem Commun,1987,(8):565-567
[78]
WU G, GEIB S J, RHEINGOLD A L, HECK R F.Isoquinolinium salt syntheses from cyclopalladated benzaldimines and alkynes[J].J Org Chem,1988,53(14):3238-3241
[79]
ROESCH K R, LAROCK R C.Synthesis of isoquinolines and pyridines by the Palladium- and Copper-catalyzed coupling and cyclization of terminal acetylenes[J].Org Lett,1999,1(4):553-556
[80]
ROESCH K R, ZHANG H, LAROCK R C.Synthesis of isoquinolines and pyridines by the Palladium-catalyzed iminoannulation of internal alkynes[J].J Org Chem,2001,66(24):8042-
[81]
DAI G, LAROCK R C.Synthesis of 3,4-disubstituted isoquinolines via Palladium-catalyzed cross-coupling of o-(1-Alkynyl)benzaldimines and organic halides[J].Org Lett,2001,3(25):4035-4038
[82]
DAI G, LAROCK R C.Synthesis of 3-substituted 4-aroylisoquinolines via Pd-catalyzed carbonylative cyclization of o-(1-alkynyl)benzaldimines[J].Org Lett,2002,4(2):193-196
[83]
HUANG Q H, LAROCK R C.Synthesis of 4-(1-Alkenyl)isoquinolines by Palladium(II)-catalyzedcyclization/olefina
[84]
tion[J].J Org Chem, 2003, 68(3): 980-988
[85]
KONNO T, CHAE J, MIYABE T, et al.Regioselective one-step synthesis of 4-fluoro-alkylatedisoquinolines via carbopalladation reaction of fluorine-containing alkynes[J].J Org Chem,2005,70(24):10172-10174
[86]
FLORENTINO L, AZNAER F, VALDES C.Synthesis of polysubstituted isoquinolines through cross-coupling reactions with r-alkoxytosylhydrazones[J].Org Lett,2012,14(9):2323-2325
[87]
YANG D Q, BURUGUPALLI S, DANIEL D, et al.Microwave-assisted one-pot synthesis of isoquinolines, furopyridines, and thienopyridines by Palladium-catalyzed sequential coupling imination annulation of 2-bromoarylaldehydes with terminal acetylenes and ammonium acetate[J].J Org Chem,2012,77(9):4466-4472
[88]
GAO K, WU J.Synthesis of functionalized 1,2-dihydroisoquinolines via multicomponent one-pot reaction of 2-alkynylbenzaldehyde, amine, zinc, and allylic bromide or benzyl bromide[J].J Org Chem,2007,72(22):8611-8613
[89]
WANG B, LU B, JIANG Y W, et al.Assembly of isoquinolines via CuI-catalyzed coupling of β-keto esters and 2-halobenzylamines[J].Org Lett,2008,10(13):2761-2763
[90]
YU X X, WU J.Synthesis of functionalized isoquinolines via sequential cyclization/cross-coupling reactions[J].J Comb Chem,2009,11(5):895-899
[91]
DING Q P, WU J.Lewis acid- and organocatalyst-cocatalyzed multicomponent reactions of 2-alkynylbenzaldehydes, amines, and ketones[J].Org Lett,2007,9(24):4959-4962
[92]
NIU Y N, YAN Y Z, GAO G L, et al.Synthesis of isoquinoline derivatives via Ag-catalyzed cyclization of 2-alkynyl benzyl azides[J].J Org Chem,2009,74(7):2893-2896
[93]
YU X X, WU J.Synthesis of 1-(1H-indol-3-yl)-1,2-dihydroisoquinolines via AgOTf-catalyzed three component reactions of 2-alkynylbenzaldehydes, amines, and indoles[J].J Comb Chem,2010,12(2):238-244
[94]
REDDY M V R, RAO M R, RHODES D, et al.Lamellarin α 20-Sulfate, an inhibitor of HIV-1 integrase active against HIV-1 virus in cell culture[J].J Med Chem,1999,42(11):1901-1907
[95]
AUBRY A, PAN X S, FISHER L M, et al.Mycobacterium tuberculosis DNA gyrase: interaction with quinolones and correlation with antimycobacterial drug activity[J].Antimicrob Agents Chemother,2004,48(4):1281-1288
[96]
BAILLY C.Lamellarins, from A to Z: A family of anticancer marine pyrrole alkaloids[J].Curr Med Chem,2004,4(4):363-378
[97]
CHEN Z Y, WU J.Efficient generation of biologically active H-pyrazolo[5,1- a]isoquinolines via multicomponent reaction[J].Org Lett,2010,12(21):4856-4859
[98]
ZHENG D Q, LI S Y, WU J.An unexpected silver triflate catalyzed reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate[J].Org Lett,2012,14(11):2655-2657
[99]
LIM S G, LEE J H, MOON C W, et al.Rh(I)-catalyzed direct ortho-alkenylation of aromatic ketimines with alkynes and its application to the synthesis of isoquinoline derivatives[J].Org Lett,2003,5(15):2759-2761
[100]
GUIMOND N, FAGNOU K.Isoquinoline synthesis via rhodium-catalyzed oxidative cross-coupling/cyclization of aryl aldimines and alkynes[J].J Am Chem Soc,2009,131(34):12050-12051
[101]
TOO P C, WANG Y F, CHIBA S.Rhodium(III)-catalyzed synthesis of isoquinolines from aryl ketone o-acyloxime derivatives and internal alkynes[J].Org Lett,2010,12(24):5688-5691
[102]
TOO P C, CHUA S H, WONG S H, et al.Synthesis of azaheterocycles from aryl ketone o-acetyl oximes and internal alkynes by Cu - Rh bimetallic relay catalysts[J].J Org Chem,2011,76(15):6159-6168
[103]
WANG B, LU B, JIANG Y W, et al.Assembly of isoquinolines via CuI-catalyzed coupling of β-keto esters and 2-halobenzylamines[J].Org Lett,2008,10(13):2761-2763
[104]
YU X X, WU J.Synthesis of functionalized isoquinolines via sequential cyclization/cross-coupling reactions[J].J Comb Chem,2009,11(5):895-899
[105]
DING Q P, WU J.Lewis acid- and organocatalyst-cocatalyzed multicomponent reactions of 2-alkynylbenzaldehydes, amines, and ketones[J].Org Lett,2007,9(24):4959-4962
[106]
NIU Y N, YAN Y Z, GAO G L, et al.Synthesis of isoquinoline derivatives via Ag-catalyzed cyclization of 2-alkynyl benzyl azides[J].J Org Chem,2009,74(7):2893-2896
[107]
YU X X, WU J.Synthesis of 1-(1H-indol-3-yl)-1,2-dihydroisoquinolines via AgOTf-catalyzed three component reactions of 2-alkynylbenzaldehydes, amines, and indoles[J].J Comb Chem,2010,12(2):238-244
[108]
REDDY M V R, RAO M R, RHODES D, et al.Lamellarin α 20-Sulfate, an inhibitor of HIV-1 integrase active against HIV-1 virus in cell culture[J].J Med Chem,1999,42(11):1901-1907
[109]
AUBRY A, PAN X S, FISHER L M, et al.Mycobacterium tuberculosis DNA gyrase: interaction with quinolones and correlation with antimycobacterial drug activity[J].Antimicrob Agents Chemother,2004,48(4):1281-1288
[110]
BAILLY C.Lamellarins, from A to Z: A family of anticancer marine pyrrole alkaloids[J].Curr Med Chem,2004,4(4):363-378
[111]
CHEN Z Y, WU J.Efficient generation of biologically active H-pyrazolo[5,1- a]isoquinolines via multicomponent reaction[J].Org Lett,2010,12(21):4856-4859
[112]
ZHENG D Q, LI S Y, WU J.An unexpected silver triflate catalyzed reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate[J].Org Lett,2012,14(11):2655-2657
[113]
LIM S G, LEE J H, MOON C W, et al.Rh(I)-catalyzed direct ortho-alkenylation of aromatic ketimines with alkynes and its application to the synthesis of isoquinoline derivatives[J].Org Lett,2003,5(15):2759-2761
[114]
GUIMOND N, FAGNOU K.Isoquinoline synthesis via rhodium-catalyzed oxidative cross-coupling/cyclization of aryl aldimines and alkynes[J].J Am Chem Soc,2009,131(34):12050-12051
[115]
TOO P C, WANG Y F, CHIBA S.Rhodium(III)-catalyzed synthesis of isoquinolines from aryl ketone o-acyloxime derivatives and internal alkynes[J].Org Lett,2010,12(24):5688-5691
[116]
TOO P C, CHUA S H, WONG S H, et al.Synthesis of azaheterocycles from aryl ketone o-acetyl oximes and internal alkynes by Cu - Rh bimetallic relay catalysts[J].J Org Chem,2011,76(15):6159-6168
[117]
WEI X H, ZHAO M, DU Z Y, et al.Synthesis of 1-aminoisoquinolines via Rh(III)-catalyzed oxidative coupling[J].Org Lett,2011,13(17):4636-4639
[118]
ZHENG L Y, JU J, BIN Y H, et al.Synthesis of isoquinolines and heterocycle-fused pyridines via three-component cascade reaction of arylk etones, hydroxylamine, and alkynes[J].J Org Chem,2012,77(13):5794-5800
[119]
KISHOR P, JEGANMOHAN M.Highly regio- and stereoselective ruthenium(II)-catalyzed direct ortho-alkenylation of aromatic and heteroaromatic aldehydes with activated alkenes under open atmosphere[J].Org Lett,2012,14(4):1134-1137
[120]
KISHOR P, JEGANMOHAN M.Ruthenium-catalyzed ortho-alkenylation of aromatic ketones with alkenes by C–H bond activation[J].Org Lett,2011,13(23):6144-6147
[121]
CHINNAGOLLA R K, PIMPARKAR S, JEGANMOHAN M.Ruthenium-catalyzed highly regioselective cyclization of ketoximes with alkynes by C- H bond activation: a practical route to synthesize substituted isoquinolines[J].Org Lett,2012,14(12):3032-3035
[122]
KORNHAA? C, LI J, ACKERANN L.Cationic Ruthenium catalysts for alkyne annulations with oximes by C?H/N?O functionalizations[J].J Org Chem,2012,77(20):9190-9198
[123]
KORIVI R P, CHENG C H.Highly efficient synthesis of isoquinolines via Nickel-catalyzed annulation of 2-iodobenzaldimines with alkynes: evidence for dual pathways of alkyne insertion[J].Org Lett,2005,7(23):5179-5182
[124]
OKAMOTO N, TAKEDA K, YANADA R.Platinum-catalyzed, one-pot tandem synthesis of indoles and isoquinolines via sequential rearrangement of amides and aminocyclization[J].J Org Chem,2010,75(22):7615-7625
[125]
MMARTINE C D, ALAIN C, DANIELE C, et al.Diphenyl quinolines and isoquinolines: synthesis and primary biological evaluation[J].Bioorg Med Chem,2000,8(11):2629-2641
[126]
YYANG Y Y, SHOU W G, CHEN Z B, et al.A tandem approach to isoquinolines from 2-azido-3-arylacrylates and α-diazocarbonyl compounds[J].J Org Chem,2008,73(10):3928-3930
[127]
PPANDY G, BALAKRISHNAN M.Suzuki cross-coupling/reductive debenzyloxycarbonylation sequence for the syntheses of [c]annulated isoquinolines: application for the syntheses of pancratistatin-like isoquinolines[J].J Org Chem,2008,73(20):8128-8131
[128]
IISHIKAWA T, SHIMOOKA K, NARIOKA T, et al.Anomalous substituent effects in the Bischler?Napieralski reaction of 2-aryl aromatic formamides[J].J Org Chem,2000,65(26):9143-9151
[129]
SSOTOMAYOR N, DOMINGUEZ E.Bischler?Napieralski cyclization?N/C-alkylation sequences for the construction of isoquinoline alkaloidsSynthesis of protoberberines and penzo[c]phenanthridines via C-2’-functionalized 3-arylisoquinolines[J].. J Org Chem,1996,61(12):4062-4072
[130]
YYOUN S W.Development of the Pictet?Spengler reaction catalyzed by AuCl3/AgOTf[J].J Org Chem,2006,71(6):2521-2523
[131]
CCHRZANOWSKA M, ROZWADOWSKA M D.Asymmetric synthesis of isoquinoline alkaloids[J].Chem Rev,2004,104(7):3341-3370
[132]
BBOUDOU M, EENDERS D.Asymmetric synthesis of tetrahydropalmatine via tandem 1,2-addition/cyclization[J].J Org Chem,2005,70(23):9486-9494
[133]
WALKER E R, LEUNG S Y, BARRETT A G M.Studies towards the total synthesis of Sch 56036; isoquinolinone synthesis and the synthesis of phenanthrenes[J].Tetrahedron Lett,2005,46(38):6537-6540
[134]
ROESCH K R, LAROCK R C.Synthesis of isoquinolines and pyridines via Palladium-catalyzed iminoannulation of internal acetylenes[J].J Org Chem,1998,63(1):5306-5307
[135]
GIRLING I R, WIDDOMSON D A.Cyclopalladated imines in synthesis 2: a new synthesis of isoquinolines[J].Tetrahedron Lett,1982,23(41):4281-4284
[136]
MAASSARANI F, PFEFFER M, LEBORGNE G.Control of the reactivity of cyclopalladated complexes for the synthesis of heterocyclic compounds[J].J Chem Soc Chem Commun,1987,(8):565-567
[137]
WU G, GEIB S J, RHEINGOLD A L, HECK R F.Isoquinolinium salt syntheses from cyclopalladated benzaldimines and alkynes[J].J Org Chem,1988,53(14):3238-3241
[138]
ROESCH K R, LAROCK R C.Synthesis of isoquinolines and pyridines by the Palladium- and Copper-catalyzed coupling and cyclization of terminal acetylenes[J].Org Lett,1999,1(4):553-556
[139]
ROESCH K R, ZHANG H, LAROCK R C.Synthesis of isoquinolines and pyridines by the Palladium-catalyzed iminoannulation of internal alkynes[J].J Org Chem,2001,66(24):8042-
[140]
DAI G, LAROCK R C.Synthesis of 3,4-disubstituted isoquinolines via Palladium-catalyzed cross-coupling of o-(1-Alkynyl)benzaldimines and organic halides[J].Org Lett,2001,3(25):4035-4038
[141]
DAI G, LAROCK R C.Synthesis of 3-substituted 4-aroylisoquinolines via Pd-catalyzed carbonylative cyclization of o-(1-alkynyl)benzaldimines[J].Org Lett,2002,4(2):193-196
[142]
HUANG Q H, LAROCK R C.Synthesis of 4-(1-Alkenyl)isoquinolines by Palladium(II)-catalyzedcyclization/olefina
[143]
tion[J].J Org Chem, 2003, 68(3): 980-988
[144]
KONNO T, CHAE J, MIYABE T, et al.Regioselective one-step synthesis of 4-fluoro-alkylatedisoquinolines via carbopalladation reaction of fluorine-containing alkynes[J].J Org Chem,2005,70(24):10172-10174
[145]
FLORENTINO L, AZNAER F, VALDES C.Synthesis of polysubstituted isoquinolines through cross-coupling reactions with r-alkoxytosylhydrazones[J].Org Lett,2012,14(9):2323-2325
[146]
YANG D Q, BURUGUPALLI S, DANIEL D, et al.Microwave-assisted one-pot synthesis of isoquinolines, furopyridines, and thienopyridines by Palladium-catalyzed sequential coupling imination annulation of 2-bromoarylaldehydes with terminal acetylenes and ammonium acetate[J].J Org Chem,2012,77(9):4466-4472
[147]
GAO K, WU J.Synthesis of functionalized 1,2-dihydroisoquinolines via multicomponent one-pot reaction of 2-alkynylbenzaldehyde, amine, zinc, and allylic bromide or benzyl bromide[J].J Org Chem,2007,72(22):8611-8613
[148]
WANG B, LU B, JIANG Y W, et al.Assembly of isoquinolines via CuI-catalyzed coupling of β-keto esters and 2-halobenzylamines[J].Org Lett,2008,10(13):2761-2763
[149]
YU X X, WU J.Synthesis of functionalized isoquinolines via sequential cyclization/cross-coupling reactions[J].J Comb Chem,2009,11(5):895-899
[150]
DING Q P, WU J.Lewis acid- and organocatalyst-cocatalyzed multicomponent reactions of 2-alkynylbenzaldehydes, amines, and ketones[J].Org Lett,2007,9(24):4959-4962
[151]
NIU Y N, YAN Y Z, GAO G L, et al.Synthesis of isoquinoline derivatives via Ag-catalyzed cyclization of 2-alkynyl benzyl azides[J].J Org Chem,2009,74(7):2893-2896
[152]
YU X X, WU J.Synthesis of 1-(1H-indol-3-yl)-1,2-dihydroisoquinolines via AgOTf-catalyzed three component reactions of 2-alkynylbenzaldehydes, amines, and indoles[J].J Comb Chem,2010,12(2):238-244
[153]
REDDY M V R, RAO M R, RHODES D, et al.Lamellarin α 20-Sulfate, an inhibitor of HIV-1 integrase active against HIV-1 virus in cell culture[J].J Med Chem,1999,42(11):1901-1907
[154]
AUBRY A, PAN X S, FISHER L M, et al.Mycobacterium tuberculosis DNA gyrase: interaction with quinolones and correlation with antimycobacterial drug activity[J].Antimicrob Agents Chemother,2004,48(4):1281-1288
[155]
BAILLY C.Lamellarins, from A to Z: A family of anticancer marine pyrrole alkaloids[J].Curr Med Chem,2004,4(4):363-378
[156]
CHEN Z Y, WU J.Efficient generation of biologically active H-pyrazolo[5,1- a]isoquinolines via multicomponent reaction[J].Org Lett,2010,12(21):4856-4859
[157]
ZHENG D Q, LI S Y, WU J.An unexpected silver triflate catalyzed reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate[J].Org Lett,2012,14(11):2655-2657
[158]
LIM S G, LEE J H, MOON C W, et al.Rh(I)-catalyzed direct ortho-alkenylation of aromatic ketimines with alkynes and its application to the synthesis of isoquinoline derivatives[J].Org Lett,2003,5(15):2759-2761
[159]
GUIMOND N, FAGNOU K.Isoquinoline synthesis via rhodium-catalyzed oxidative cross-coupling/cyclization of aryl aldimines and alkynes[J].J Am Chem Soc,2009,131(34):12050-12051
[160]
TOO P C, WANG Y F, CHIBA S.Rhodium(III)-catalyzed synthesis of isoquinolines from aryl ketone o-acyloxime derivatives and internal alkynes[J].Org Lett,2010,12(24):5688-5691
[161]
TOO P C, CHUA S H, WONG S H, et al.Synthesis of azaheterocycles from aryl ketone o-acetyl oximes and internal alkynes by Cu - Rh bimetallic relay catalysts[J].J Org Chem,2011,76(15):6159-6168
[162]
WEI X H, ZHAO M, DU Z Y, et al.Synthesis of 1-aminoisoquinolines via Rh(III)-catalyzed oxidative coupling[J].Org Lett,2011,13(17):4636-4639
[163]
ZHENG L Y, JU J, BIN Y H, et al.Synthesis of isoquinolines and heterocycle-fused pyridines via three-component cascade reaction of arylk etones, hydroxylamine, and alkynes[J].J Org Chem,2012,77(13):5794-5800
[164]
CCHRZANOWSKA M, ROZWADOWSKA M D.Asymmetric synthesis of isoquinoline alkaloids[J].Chem Rev,2004,104(7):3341-3370
[165]
WANG B, LU B, JIANG Y W, et al.Assembly of isoquinolines via CuI-catalyzed coupling of β-keto esters and 2-halobenzylamines[J].Org Lett,2008,10(13):2761-2763
[166]
BBOUDOU M, EENDERS D.Asymmetric synthesis of tetrahydropalmatine via tandem 1,2-addition/cyclization[J].J Org Chem,2005,70(23):9486-9494
[167]
WALKER E R, LEUNG S Y, BARRETT A G M.Studies towards the total synthesis of Sch 56036; isoquinolinone synthesis and the synthesis of phenanthrenes[J].Tetrahedron Lett,2005,46(38):6537-6540
[168]
ROESCH K R, LAROCK R C.Synthesis of isoquinolines and pyridines via Palladium-catalyzed iminoannulation of internal acetylenes[J].J Org Chem,1998,63(1):5306-5307
[169]
YU X X, WU J.Synthesis of functionalized isoquinolines via sequential cyclization/cross-coupling reactions[J].J Comb Chem,2009,11(5):895-899
[170]
GIRLING I R, WIDDOMSON D A.Cyclopalladated imines in synthesis 2: a new synthesis of isoquinolines[J].Tetrahedron Lett,1982,23(41):4281-4284
[171]
DING Q P, WU J.Lewis acid- and organocatalyst-cocatalyzed multicomponent reactions of 2-alkynylbenzaldehydes, amines, and ketones[J].Org Lett,2007,9(24):4959-4962
[172]
MAASSARANI F, PFEFFER M, LEBORGNE G.Control of the reactivity of cyclopalladated complexes for the synthesis of heterocyclic compounds[J].J Chem Soc Chem Commun,1987,(8):565-567
[173]
NIU Y N, YAN Y Z, GAO G L, et al.Synthesis of isoquinoline derivatives via Ag-catalyzed cyclization of 2-alkynyl benzyl azides[J].J Org Chem,2009,74(7):2893-2896
[174]
WU G, GEIB S J, RHEINGOLD A L, HECK R F.Isoquinolinium salt syntheses from cyclopalladated benzaldimines and alkynes[J].J Org Chem,1988,53(14):3238-3241
[175]
YU X X, WU J.Synthesis of 1-(1H-indol-3-yl)-1,2-dihydroisoquinolines via AgOTf-catalyzed three component reactions of 2-alkynylbenzaldehydes, amines, and indoles[J].J Comb Chem,2010,12(2):238-244
[176]
ROESCH K R, LAROCK R C.Synthesis of isoquinolines and pyridines by the Palladium- and Copper-catalyzed coupling and cyclization of terminal acetylenes[J].Org Lett,1999,1(4):553-556
[177]
REDDY M V R, RAO M R, RHODES D, et al.Lamellarin α 20-Sulfate, an inhibitor of HIV-1 integrase active against HIV-1 virus in cell culture[J].J Med Chem,1999,42(11):1901-1907
[178]
ROESCH K R, ZHANG H, LAROCK R C.Synthesis of isoquinolines and pyridines by the Palladium-catalyzed iminoannulation of internal alkynes[J].J Org Chem,2001,66(24):8042-
[179]
AUBRY A, PAN X S, FISHER L M, et al.Mycobacterium tuberculosis DNA gyrase: interaction with quinolones and correlation with antimycobacterial drug activity[J].Antimicrob Agents Chemother,2004,48(4):1281-1288
[180]
DAI G, LAROCK R C.Synthesis of 3,4-disubstituted isoquinolines via Palladium-catalyzed cross-coupling of o-(1-Alkynyl)benzaldimines and organic halides[J].Org Lett,2001,3(25):4035-4038
[181]
BAILLY C.Lamellarins, from A to Z: A family of anticancer marine pyrrole alkaloids[J].Curr Med Chem,2004,4(4):363-378
[182]
DAI G, LAROCK R C.Synthesis of 3-substituted 4-aroylisoquinolines via Pd-catalyzed carbonylative cyclization of o-(1-alkynyl)benzaldimines[J].Org Lett,2002,4(2):193-196
[183]
HUANG Q H, LAROCK R C.Synthesis of 4-(1-Alkenyl)isoquinolines by Palladium(II)-catalyzedcyclization/olefina
[184]
tion[J].J Org Chem, 2003, 68(3): 980-988
[185]
CHEN Z Y, WU J.Efficient generation of biologically active H-pyrazolo[5,1- a]isoquinolines via multicomponent reaction[J].Org Lett,2010,12(21):4856-4859
[186]
KONNO T, CHAE J, MIYABE T, et al.Regioselective one-step synthesis of 4-fluoro-alkylatedisoquinolines via carbopalladation reaction of fluorine-containing alkynes[J].J Org Chem,2005,70(24):10172-10174
[187]
ZHENG D Q, LI S Y, WU J.An unexpected silver triflate catalyzed reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate[J].Org Lett,2012,14(11):2655-2657
[188]
FLORENTINO L, AZNAER F, VALDES C.Synthesis of polysubstituted isoquinolines through cross-coupling reactions with r-alkoxytosylhydrazones[J].Org Lett,2012,14(9):2323-2325
[189]
LIM S G, LEE J H, MOON C W, et al.Rh(I)-catalyzed direct ortho-alkenylation of aromatic ketimines with alkynes and its application to the synthesis of isoquinoline derivatives[J].Org Lett,2003,5(15):2759-2761
[190]
YANG D Q, BURUGUPALLI S, DANIEL D, et al.Microwave-assisted one-pot synthesis of isoquinolines, furopyridines, and thienopyridines by Palladium-catalyzed sequential coupling imination annulation of 2-bromoarylaldehydes with terminal acetylenes and ammonium acetate[J].J Org Chem,2012,77(9):4466-4472
[191]
GUIMOND N, FAGNOU K.Isoquinoline synthesis via rhodium-catalyzed oxidative cross-coupling/cyclization of aryl aldimines and alkynes[J].J Am Chem Soc,2009,131(34):12050-12051
[192]
GAO K, WU J.Synthesis of functionalized 1,2-dihydroisoquinolines via multicomponent one-pot reaction of 2-alkynylbenzaldehyde, amine, zinc, and allylic bromide or benzyl bromide[J].J Org Chem,2007,72(22):8611-8613
[193]
MMARTINE C D, ALAIN C, DANIELE C, et al.Diphenyl quinolines and isoquinolines: synthesis and primary biological evaluation[J].Bioorg Med Chem,2000,8(11):2629-2641
[194]
YYANG Y Y, SHOU W G, CHEN Z B, et al.A tandem approach to isoquinolines from 2-azido-3-arylacrylates and α-diazocarbonyl compounds[J].J Org Chem,2008,73(10):3928-3930
[195]
PPANDY G, BALAKRISHNAN M.Suzuki cross-coupling/reductive debenzyloxycarbonylation sequence for the syntheses of [c]annulated isoquinolines: application for the syntheses of pancratistatin-like isoquinolines[J].J Org Chem,2008,73(20):8128-8131
[196]
IISHIKAWA T, SHIMOOKA K, NARIOKA T, et al.Anomalous substituent effects in the Bischler?Napieralski reaction of 2-aryl aromatic formamides[J].J Org Chem,2000,65(26):9143-9151
[197]
SSOTOMAYOR N, DOMINGUEZ E.Bischler?Napieralski cyclization?N/C-alkylation sequences for the construction of isoquinoline alkaloidsSynthesis of protoberberines and penzo[c]phenanthridines via C-2’-functionalized 3-arylisoquinolines[J].. J Org Chem,1996,61(12):4062-4072
[198]
YYOUN S W.Development of the Pictet?Spengler reaction catalyzed by AuCl3/AgOTf[J].J Org Chem,2006,71(6):2521-2523
[199]
CCHRZANOWSKA M, ROZWADOWSKA M D.Asymmetric synthesis of isoquinoline alkaloids[J].Chem Rev,2004,104(7):3341-3370
[200]
BBOUDOU M, EENDERS D.Asymmetric synthesis of tetrahydropalmatine via tandem 1,2-addition/cyclization[J].J Org Chem,2005,70(23):9486-9494
[201]
WALKER E R, LEUNG S Y, BARRETT A G M.Studies towards the total synthesis of Sch 56036; isoquinolinone synthesis and the synthesis of phenanthrenes[J].Tetrahedron Lett,2005,46(38):6537-6540
[202]
ROESCH K R, LAROCK R C.Synthesis of isoquinolines and pyridines via Palladium-catalyzed iminoannulation of internal acetylenes[J].J Org Chem,1998,63(1):5306-5307
[203]
GIRLING I R, WIDDOMSON D A.Cyclopalladated imines in synthesis 2: a new synthesis of isoquinolines[J].Tetrahedron Lett,1982,23(41):4281-4284
[204]
MAASSARANI F, PFEFFER M, LEBORGNE G.Control of the reactivity of cyclopalladated complexes for the synthesis of heterocyclic compounds[J].J Chem Soc Chem Commun,1987,(8):565-567
[205]
WU G, GEIB S J, RHEINGOLD A L, HECK R F.Isoquinolinium salt syntheses from cyclopalladated benzaldimines and alkynes[J].J Org Chem,1988,53(14):3238-3241
[206]
ROESCH K R, LAROCK R C.Synthesis of isoquinolines and pyridines by the Palladium- and Copper-catalyzed coupling and cyclization of terminal acetylenes[J].Org Lett,1999,1(4):553-556
[207]
ROESCH K R, ZHANG H, LAROCK R C.Synthesis of isoquinolines and pyridines by the Palladium-catalyzed iminoannulation of internal alkynes[J].J Org Chem,2001,66(24):8042-
[208]
DAI G, LAROCK R C.Synthesis of 3,4-disubstituted isoquinolines via Palladium-catalyzed cross-coupling of o-(1-Alkynyl)benzaldimines and organic halides[J].Org Lett,2001,3(25):4035-4038
[209]
YU X X, WU J.Synthesis of functionalized isoquinolines via sequential cyclization/cross-coupling reactions[J].J Comb Chem,2009,11(5):895-899
[210]
DING Q P, WU J.Lewis acid- and organocatalyst-cocatalyzed multicomponent reactions of 2-alkynylbenzaldehydes, amines, and ketones[J].Org Lett,2007,9(24):4959-4962
[211]
NIU Y N, YAN Y Z, GAO G L, et al.Synthesis of isoquinoline derivatives via Ag-catalyzed cyclization of 2-alkynyl benzyl azides[J].J Org Chem,2009,74(7):2893-2896
[212]
YU X X, WU J.Synthesis of 1-(1H-indol-3-yl)-1,2-dihydroisoquinolines via AgOTf-catalyzed three component reactions of 2-alkynylbenzaldehydes, amines, and indoles[J].J Comb Chem,2010,12(2):238-244
[213]
REDDY M V R, RAO M R, RHODES D, et al.Lamellarin α 20-Sulfate, an inhibitor of HIV-1 integrase active against HIV-1 virus in cell culture[J].J Med Chem,1999,42(11):1901-1907
[214]
AUBRY A, PAN X S, FISHER L M, et al.Mycobacterium tuberculosis DNA gyrase: interaction with quinolones and correlation with antimycobacterial drug activity[J].Antimicrob Agents Chemother,2004,48(4):1281-1288
[215]
BAILLY C.Lamellarins, from A to Z: A family of anticancer marine pyrrole alkaloids[J].Curr Med Chem,2004,4(4):363-378
[216]
CHEN Z Y, WU J.Efficient generation of biologically active H-pyrazolo[5,1- a]isoquinolines via multicomponent reaction[J].Org Lett,2010,12(21):4856-4859
[217]
ZHENG D Q, LI S Y, WU J.An unexpected silver triflate catalyzed reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate[J].Org Lett,2012,14(11):2655-2657
[218]
LIM S G, LEE J H, MOON C W, et al.Rh(I)-catalyzed direct ortho-alkenylation of aromatic ketimines with alkynes and its application to the synthesis of isoquinoline derivatives[J].Org Lett,2003,5(15):2759-2761
[219]
GUIMOND N, FAGNOU K.Isoquinoline synthesis via rhodium-catalyzed oxidative cross-coupling/cyclization of aryl aldimines and alkynes[J].J Am Chem Soc,2009,131(34):12050-12051
[220]
TOO P C, WANG Y F, CHIBA S.Rhodium(III)-catalyzed synthesis of isoquinolines from aryl ketone o-acyloxime derivatives and internal alkynes[J].Org Lett,2010,12(24):5688-5691
[221]
WEI X H, ZHAO M, DU Z Y, et al.Synthesis of 1-aminoisoquinolines via Rh(III)-catalyzed oxidative coupling[J].Org Lett,2011,13(17):4636-4639
[222]
ZHENG L Y, JU J, BIN Y H, et al.Synthesis of isoquinolines and heterocycle-fused pyridines via three-component cascade reaction of arylk etones, hydroxylamine, and alkynes[J].J Org Chem,2012,77(13):5794-5800
[223]
KISHOR P, JEGANMOHAN M.Highly regio- and stereoselective ruthenium(II)-catalyzed direct ortho-alkenylation of aromatic and heteroaromatic aldehydes with activated alkenes under open atmosphere[J].Org Lett,2012,14(4):1134-1137
[224]
KISHOR P, JEGANMOHAN M.Ruthenium-catalyzed ortho-alkenylation of aromatic ketones with alkenes by C–H bond activation[J].Org Lett,2011,13(23):6144-6147
[225]
CHINNAGOLLA R K, PIMPARKAR S, JEGANMOHAN M.Ruthenium-catalyzed highly regioselective cyclization of ketoximes with alkynes by C- H bond activation: a practical route to synthesize substituted isoquinolines[J].Org Lett,2012,14(12):3032-3035
[226]
KORNHAA? C, LI J, ACKERANN L.Cationic Ruthenium catalysts for alkyne annulations with oximes by C?H/N?O functionalizations[J].J Org Chem,2012,77(20):9190-9198
[227]
KORIVI R P, CHENG C H.Highly efficient synthesis of isoquinolines via Nickel-catalyzed annulation of 2-iodobenzaldimines with alkynes: evidence for dual pathways of alkyne insertion[J].Org Lett,2005,7(23):5179-5182
[228]
OKAMOTO N, TAKEDA K, YANADA R.Platinum-catalyzed, one-pot tandem synthesis of indoles and isoquinolines via sequential rearrangement of amides and aminocyclization[J].J Org Chem,2010,75(22):7615-7625
[229]
BBENTLEY K W.The Isoquinoline alkaloids[M]. Amsterdam: Harwood academic publishers, 1998
[230]
MMARTINE C D, ALAIN C, DANIELE C, et al.Diphenyl quinolines and isoquinolines: synthesis and primary biological evaluation[J].Bioorg Med Chem,2000,8(11):2629-2641
[231]
YYANG Y Y, SHOU W G, CHEN Z B, et al.A tandem approach to isoquinolines from 2-azido-3-arylacrylates and α-diazocarbonyl compounds[J].J Org Chem,2008,73(10):3928-3930
[232]
PPANDY G, BALAKRISHNAN M.Suzuki cross-coupling/reductive debenzyloxycarbonylation sequence for the syntheses of [c]annulated isoquinolines: application for the syntheses of pancratistatin-like isoquinolines[J].J Org Chem,2008,73(20):8128-8131
[233]
IISHIKAWA T, SHIMOOKA K, NARIOKA T, et al.Anomalous substituent effects in the Bischler?Napieralski reaction of 2-aryl aromatic formamides[J].J Org Chem,2000,65(26):9143-9151
[234]
SSOTOMAYOR N, DOMINGUEZ E.Bischler?Napieralski cyclization?N/C-alkylation sequences for the construction of isoquinoline alkaloidsSynthesis of protoberberines and penzo[c]phenanthridines via C-2’-functionalized 3-arylisoquinolines[J].. J Org Chem,1996,61(12):4062-4072
[235]
YYOUN S W.Development of the Pictet?Spengler reaction catalyzed by AuCl3/AgOTf[J].J Org Chem,2006,71(6):2521-2523
[236]
CCHRZANOWSKA M, ROZWADOWSKA M D.Asymmetric synthesis of isoquinoline alkaloids[J].Chem Rev,2004,104(7):3341-3370
[237]
BBOUDOU M, EENDERS D.Asymmetric synthesis of tetrahydropalmatine via tandem 1,2-addition/cyclization[J].J Org Chem,2005,70(23):9486-9494
[238]
WALKER E R, LEUNG S Y, BARRETT A G M.Studies towards the total synthesis of Sch 56036; isoquinolinone synthesis and the synthesis of phenanthrenes[J].Tetrahedron Lett,2005,46(38):6537-6540
[239]
ROESCH K R, LAROCK R C.Synthesis of isoquinolines and pyridines via Palladium-catalyzed iminoannulation of internal acetylenes[J].J Org Chem,1998,63(1):5306-5307
[240]
GIRLING I R, WIDDOMSON D A.Cyclopalladated imines in synthesis 2: a new synthesis of isoquinolines[J].Tetrahedron Lett,1982,23(41):4281-4284
[241]
MAASSARANI F, PFEFFER M, LEBORGNE G.Control of the reactivity of cyclopalladated complexes for the synthesis of heterocyclic compounds[J].J Chem Soc Chem Commun,1987,(8):565-567
[242]
WU G, GEIB S J, RHEINGOLD A L, HECK R F.Isoquinolinium salt syntheses from cyclopalladated benzaldimines and alkynes[J].J Org Chem,1988,53(14):3238-3241
[243]
ROESCH K R, LAROCK R C.Synthesis of isoquinolines and pyridines by the Palladium- and Copper-catalyzed coupling and cyclization of terminal acetylenes[J].Org Lett,1999,1(4):553-556
[244]
ROESCH K R, ZHANG H, LAROCK R C.Synthesis of isoquinolines and pyridines by the Palladium-catalyzed iminoannulation of internal alkynes[J].J Org Chem,2001,66(24):8042-
[245]
DAI G, LAROCK R C.Synthesis of 3,4-disubstituted isoquinolines via Palladium-catalyzed cross-coupling of o-(1-Alkynyl)benzaldimines and organic halides[J].Org Lett,2001,3(25):4035-4038
[246]
DAI G, LAROCK R C.Synthesis of 3-substituted 4-aroylisoquinolines via Pd-catalyzed carbonylative cyclization of o-(1-alkynyl)benzaldimines[J].Org Lett,2002,4(2):193-196
[247]
HUANG Q H, LAROCK R C.Synthesis of 4-(1-Alkenyl)isoquinolines by Palladium(II)-catalyzedcyclization/olefina
[248]
tion[J].J Org Chem, 2003, 68(3): 980-988
[249]
KONNO T, CHAE J, MIYABE T, et al.Regioselective one-step synthesis of 4-fluoro-alkylatedisoquinolines via carbopalladation reaction of fluorine-containing alkynes[J].J Org Chem,2005,70(24):10172-10174
[250]
FLORENTINO L, AZNAER F, VALDES C.Synthesis of polysubstituted isoquinolines through cross-coupling reactions with r-alkoxytosylhydrazones[J].Org Lett,2012,14(9):2323-2325
[251]
YANG D Q, BURUGUPALLI S, DANIEL D, et al.Microwave-assisted one-pot synthesis of isoquinolines, furopyridines, and thienopyridines by Palladium-catalyzed sequential coupling imination annulation of 2-bromoarylaldehydes with terminal acetylenes and ammonium acetate[J].J Org Chem,2012,77(9):4466-4472
[252]
GAO K, WU J.Synthesis of functionalized 1,2-dihydroisoquinolines via multicomponent one-pot reaction of 2-alkynylbenzaldehyde, amine, zinc, and allylic bromide or benzyl bromide[J].J Org Chem,2007,72(22):8611-8613
[253]
KISHOR P, JEGANMOHAN M.Highly regio- and stereoselective ruthenium(II)-catalyzed direct ortho-alkenylation of aromatic and heteroaromatic aldehydes with activated alkenes under open atmosphere[J].Org Lett,2012,14(4):1134-1137
[254]
KISHOR P, JEGANMOHAN M.Ruthenium-catalyzed ortho-alkenylation of aromatic ketones with alkenes by C–H bond activation[J].Org Lett,2011,13(23):6144-6147
[255]
CHINNAGOLLA R K, PIMPARKAR S, JEGANMOHAN M.Ruthenium-catalyzed highly regioselective cyclization of ketoximes with alkynes by C- H bond activation: a practical route to synthesize substituted isoquinolines[J].Org Lett,2012,14(12):3032-3035
[256]
KORNHAA? C, LI J, ACKERANN L.Cationic Ruthenium catalysts for alkyne annulations with oximes by C?H/N?O functionalizations[J].J Org Chem,2012,77(20):9190-9198
[257]
KORIVI R P, CHENG C H.Highly efficient synthesis of isoquinolines via Nickel-catalyzed annulation of 2-iodobenzaldimines with alkynes: evidence for dual pathways of alkyne insertion[J].Org Lett,2005,7(23):5179-5182
[258]
OKAMOTO N, TAKEDA K, YANADA R.Platinum-catalyzed, one-pot tandem synthesis of indoles and isoquinolines via sequential rearrangement of amides and aminocyclization[J].J Org Chem,2010,75(22):7615-7625
