全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

十二指肠乳头喷洒利多卡因对ERCP术后胰腺炎发生和血淀粉酶水平的影响

, PP. 127-129

Keywords: 利多卡因,经内镜逆行胰胆管造影术,胰腺炎,高淀粉酶血症,预防

Full-Text   Cite this paper   Add to My Lib

Abstract:

目的探讨十二指肠乳头局部喷洒利多卡因对经内镜逆行胰胆管造影(endoscopicretrogradecholangiopancreatography,ERCP)术后胰腺炎发生和血淀粉酶水平的影响。方法需要接受ERCP手术的112例患者随机分为利多卡因组和对照组,利多卡因组55例,对照组57例。前者在十二指肠乳头插管前给予10mL1%利多卡因乳头局部喷洒,后者给予生理盐水,比较两组ERCP后胰腺炎和高淀粉酶血症的发生情况。结果利多卡因组术后胰腺炎发生率(3.64%vs15.79%,P=0.031)和高淀粉酶血症发生率(18.18%vs40.35%,P=0.01)均明显低于对照组。结论十二指肠乳头局部喷洒利多卡因可以降低ERCP术后胰腺炎和高淀粉酶血症的发生。

References

[1]  Sherman S,Lehman GA. ERCPand endoscopic sphincterotomy-induced pa ncreatitis[J]. Pancreas,1991,6:350-367.
[2]  Miah AR, Bank S,Stark B,Visvalingum V, Tiscornia O. The ef fect of local lid ocaine on the ampler pressures, ease of cannulation and post-ERCP hype ramylasemia and pancreatitis[J]. Gastroenterology,2000,118:162.
[3]  Niederau C,Boxchard Ciither R, et al.Early development of exp erimental billa ry pancreatitis and its amelioration by CCK-receptor blockade[J].Hepatoga stroenterology,1996,43:1442-1453.
[4]  Sari R,Juhani S,Seppol, et al.Cholecystokinin in the early cour se of acute post-ERCP pancreastitis[J].AM Coll Surg,1999,189:560-565.
[5]  Plusezyk T,Bauer M,Marz I, et al.Comparative effects of secretin(SET )and ch olecystokinin octapeptide(CCK-8)on parcreatic microcirculation[J].Digestive Disease and Science,1995,40:1199-1206.
[6]  Louie DS,May D,Miller P,Owyang C. Cholecystokinin mediates f eedback regul ation of pa- ncreastic enzyme secretion in rats[J].Am J Physiol,1986 ,250:252-259.
[7]  McFarland RJ, Corbett CRR, Taylor P, et al.The relaxant action of hymecromon e and lingocaine on induced spasm of the bile duct sphincter[J].Br J Clin Pharmacol,1984,17:766-768.
[8]  Cavallini G,Tittobello A,Frulloni L,et al. Gabexate for the preven tion of panc reatic damage related to Endoscopic retrograde cholangiopancreatography[ J].N Eng1 Med,1996,335:919-923.
[9]  潘涛,王一平,杨锦林,等.生长抑素及其类似物奥曲肽预防内镜逆行胰胆管造影 术后胰腺炎的系统评价[J].中国循证医学杂志,2005,10(5):767-777.
[10]  Farkas G.Bedside scoring system to predict the risk of developing p ancreatitis following ERCP[J]. Endoscopy,2002,34:483-488.
[11]  Cotton PB,Lehman G,Vennes J,et al. Endoscopic sphincterotomy comp lications an d their management:an attempt at consensus[J]. Gastrointest Endosc,1991 ,37:383-393.
[12]  Katsinelos P, Kountouras J, Chatzis J, et al. High-dose allopurino l for preve ntion of post-ERCP pancreatitis: a prospective randomized double-blind controlled trial[J]. Gastrointest Endosc,2005,61:407-415.
[13]  Mcune WS,Shorb PE,Moscovitz H. Endoscopic cannulation of the ampulla of Vater: a preliminary report[J]. Ann Surg,1968,167:752-756.
[14]  Freeman ML,Sario JA,Nelson DB,et al.Risk factors for post-ERC Ppancreatit is: a prospective,multicenter study[J]. Gastrointest Endosc,2001,54 :425-434.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133