99Tcm-HL91乏氧显像诊断恶性实体肿瘤的研究进展

, PP. 551-553

Keywords: 实体肿瘤,细胞乏氧,放射性核素显像,99Tcm-HL91

Full-Text   Cite this paper   Add to My Lib

Abstract:

References

[1]	Gatenby RA,Coia LR,Richter MP,et al.Oxygen tension in human tumors:in vivo mapping using CT-guided probes[J]. Rsdiology,1985, 156:211.
[2]	Hockel M,Schlenger K,Knoop C,et al.Oxygenation of carcinomas of the uterine cervix: evaluation by compularized O2 measurements[J]. Cancer Res, 1991,51:6098.
[3]	Koumenis C,Alarcon R,Hammond E, et al. Regulation of P53 by hypoxia dissociation of transcription repression and apoptosis from P53-dependent transactivition[J]. Mol Cell Biol, 2001,21:1297-310.
[4]	Harris AL. Hypoxia―a key regulator factor in tumor growth [J]. Nat Res Cancer,2002,2:38-47.
[5]	Honess DJ,Hill SA,Collingridge DR,et al.Preclinical evaluation of the novel hypoxic marker 99Tcm-HL91(prognox)in murine and xenograft systems in vivo[J].Int J Radiat Oncol Biol Phys,1998,42(4):731-735.
[6]	国毓智,张志勇,朱霖,等.乏氧组织显像剂99Tcm-HL91冻干药盒的研制[J].同位素,16(3-4):171-173.
[7]	Yutani K,Kusuoka H,Fukuchi K,et al.Applicability of 99Tcm-HL91,a putative hypoxic tracer,to detection of tumor hypoxia[J].J Nucl Med,1999,40(5):854-861.
[8]	Jiang Ning-yi,Fan Xiao-lian,Zhu Can-shen,et al. An Animal Experiment of Tumor Imaging with 99Tcm-HL91[J]. Journal of Modern Clinical Medical Bioengineering,2003,9(1):6-8.
[9]	Ballinger JR. Imaging hypoxia in tumors[ J]. Semin Nucl Med,2001, 31(4): 321-329.
[10]	Tatsumi M, Yutani K, Kusuoka H, et al. Technetium-99m HL91uptake as a tumor hypoxia marker: relationship to tumor blood flow[J].Eur J Nucl Med, 1999,26:91-94.
[11]	Yao Z,Qu W, Zhou Y, et al. 99Tcm-HL91“hot spot”imaging of mice bearing human carcinoma by gamma camera and the effects of tumor necrosis on imaging[J]. Chin Med J,2000,113:404-407.
[12]	李舜,张家云,邓咏梅, 等. 99Tcm-HL91延迟显像在乳腺良恶性病变鉴别诊断中的价值[J].广州医学杂志,2004,32(4):39-41.
[13]	邓波,肖欢,陈小凤,等.肺癌乏氧显像的临床应用[J].中国医师杂志,2004,6(3):299-300.
[14]	曹卫,张永学. 99Tcm-HL91与99Tcm-MIBI显像在实体肿瘤和炎症模型中的对比研究[J].中华核医学杂志,2001,21(2):103-105.
[15]	王孝深,章英剑,胡超苏,等. 99Tcm-HL91与99Tcm-MIBI在鼻咽癌显像中的对比研究[J]. 肿瘤学杂志,2008,14(8):631-635.
[16]	[16〗 Kao CH,Tsai SC,Liu TJ,et al.P-Glycoprotein and multidrug resistance-related protein expressions in relation to technetium-99m methoxyisobutylisonitrile scintimammography findings[J].Cancer Res,2001,61(4):1412-1414.
[17]	Cook GJ,Houston S,Barrington SF,et al.Technetium-99m-labeled HL91 to identify tumor hypoxia:correlation with fluorine-18-FDG[J].J Nucl Med,1998,39(1):99-103.
[18]	蒋宁一,肖亦明,刘生,等. 99Tcm-HL91肿瘤乏氧显像与18F-FDG符合线路显像的比较[J].中国医学影像学杂志,2008,16(5):379-380.
[19]	毛荣虎. 99Tcm-HL91显像在骨转移瘤中的初步临床应用研究[D].郑州:郑州大学医学院,2003.
[20]	Kinuya S,Yokoyama K, Li XF, et al. Hypoxia-induced alterationof tracer accumulation in cultured cancer cells and xenografts inmice: implications for pre-therapeutic prediction of treatment out-comes with 99Tcm-sestamibi, 201TL chloride and 99Tcm-HL91[J]. Eur J Nucl Med Mol Imaging, 2002,29:1006-1011.

Full-Text