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双额脑挫裂伤患者血清S100β蛋白含量变化的临床意义

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Keywords: 双额脑挫裂伤,血清S100β蛋白,手术

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Abstract:

目的探讨双额脑挫裂伤患者血清S100β蛋白含量变化的临床意义。方法急性双额脑挫裂伤患者27例,GCS>9分,分别于伤后12h、1、2、3、5d空腹抽取外周静脉血,使用双抗体夹心ELISA法测定S100β蛋白的血清浓度。结果17例保守治疗成功,另10例均在保守治疗3d内手术,术后无死亡病例。手术患者和保守治疗患者伤后血清S100β蛋白水平均高于正常值,但手术组患者在伤后相同时间里血清S110B蛋白明显高于保守治疗组(P<0.01)。结论伤后血清高S100β且持续存在是急性双额脑挫裂伤手术的指证之一。

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