Hashimoto I, Kodama J, Seki N, et al. Vascular endothelial growth factor-C expression and its relationship to pelvic; lymph node status in invisive cervical cancer[J]. Br J Cancer, 2001,85(1):93-97. (责任编辑:路锦绣) Clinical Research on the Expression of VEGF-C in Cervical Carcinoma YANG Cai-hong1, LI Xiao-tao2, ZHANG Xue-yu1, ZHANG Yong-mei3 (1.The General Hospital of Ningxia Medical University, Yinchuan 750004; 2.Physical Examination Recovery Health center of Ningxia, Yinchuan 750004; 3.Department of Gynecology, the Second Affiliated Hospital of Ningxia Medical University, Yinchuan 750001)Abstract: Objective To investigate the clinical significance of vascular endothelial growth factor-C(VEGF-C)in cervical carcinoma and normal cervical. Methods(1)The mRNA levels of VEGF-C was detected by Real Time Fluorescence Quantitative PCR(FQ RT-PCR)method,and the serum levels was determined by enzyme linked immunosorbent assay(ELISA)in 60 cervical carcer. Results Levels of mRNA expression and concentration of serum of VEGF-C in cervical carcinoma were significantly higher
[2]
Takahashi H, Shibuya M.The vascular endothelial growth factor(VEGF)/VEGF receptor system and its role under physiological and pathological conditions[J].Clin Sci(Lond), 2005, 109(3):227-241.
[3]
Dadras SS,Lange-asschenfeldt B,Velasco P, et al. Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodes[J].Mod Pathol, 2005, 18(9):1232-1242.
[4]
Mitsuhashi A, Suzuka K,Yamazawa K,et al. Serum vascular endothelial growth factor(VEGF)and VEGF-C levels as tumormarkers in patientswith cervical carcinoma[ J]. Cancer, 2005, 103(4):724-730.
