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髋关节周围骨折并发静脉血栓性疾病临床分析

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Keywords: 髋关节周围骨折,静脉血栓性疾病,D-二聚体,纤维蛋白原

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Abstract:

目的通过分析住院髋关节周围骨折患者并发静脉血栓性疾病(venousthromboemlolism,VTE)的相关临床资料,总结该型骨折患者并发VTE的发病特点及临床防治方法。方法回顾性分析2010年5月-2011年5月期间收住124例髋关节周围骨折患者按性别分为男性和女性组,其中共29例经B超,肺动脉CT造影(CTPA)检查明确并发静脉血栓性疾病。对以上患者进行临床及血液学等相关指标对比分析。结果男性患者组血栓发病率18.8%。女性患者组28.6%,男女组间血栓性疾病发病率差异无统计学意义(P>0.05),总VTE发病率23.2%。血栓静脉性疾病患者住院周期较无血栓组延长(P<0.05),血栓组患者纤维蛋白原(Fibrinogen,FIB)值在并发VTE前后有显著性差异(P<0.05)。作为血栓性疾病特异性血液指标D-二聚体在本组病例中灵敏度72.4%;特异度74.0%。结论单纯以D-二聚体作为VTE在髋关节周围骨折患者VET诊断具有一定限制性,FIB对诊断髋关节周围骨折并发VTE有辅助作用。

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