全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

骨创伤患者IL-6和血糖动态变化及其临床意义

, PP. 80-83

Keywords: 骨创伤,白细胞介素6,血糖,动态变化

Full-Text   Cite this paper   Add to My Lib

Abstract:

目的探讨不同程度骨创伤患者血糖及白细胞介素6(interleukin-6,IL-6)的动态变化,以及骨创伤应激状态下血糖和炎性因子的相关性。方法选择本院2013年2月至8月收治的不同程度骨创伤患者105例作为观察组,同期本院体检者92例作为对照组,分别测定两组空腹血糖水平及IL-6的动态变化情况。结果不同程度骨创伤患者IL-6及空腹血糖水平不同,术前严重伤组明显高于轻伤组与重伤组(P<0.05),各组术后1、3、5、7d示严重伤组的IL-6及空腹血糖水平明显高于轻伤组与重伤组(P<0.05),各组术前与术后比较差异有统计学意义(P<0.05);各组IL-6与空腹血糖水平随时间延长呈明显正相关关系。结论骨创伤患者血糖及IL-6动态变化与骨创伤严重程度密切相关,因此检测患者血糖及IL-6水平,可有效提高对骨创伤病情的判断和改善预后。

References

[1]  Beam HA,Parsons JR,Lin SS.The effects of blood glucose control upon fracture healing in the BB Wistar rat with diabetes mellitus[J].J Orthop Res,2002,20(6):1210-1216.
[2]  美国机动车医学促进会(AAAM).简明损伤定级标准[M].重庆市急救医疗中心,译.重庆:重庆出版社,2005:1-35.
[3]  Strmmer L,Abou El-Ella G,Kamel A,et al.Upregulation of uncoupling protein homologues in skeletal muscle but not adipose tissue in posttraumatic insulin resistance[J].Biochem Biophys Res Commun,2001,281(2):334-340.
[4]  王军,王开荣.骨创伤患者血浆D二聚体和血糖水平变化及其临床意义[J].检验医学与临床,2012,9(9):1089-1091.
[5]  Jawa RS,Anillo S,Huntoon K,et al.Interleukin-6 in surgery,trauma,and critical care part II:clinical implications[J].J Intensive Care Med,2011,26(2):73-87.
[6]  Benetti E,Mastrocola R,Rogazzo M,et al.High sugar intake and development of skeletal muscle insulin resistance and inflammation in mice:a protective role for PPAR-δagonism[J].Mediators Inflamm,2013,509502,doi:10.1155/2013/509502.
[7]  Morariu AM,Loef BG,Aarts LP,et al.Dexamethasone:benefit and prejudice for patients undergoing on-pump coronary artery bypass grafting:a study on myocardial,pulmonary,renal,intestinal,and hepatic injury[J].Chest,2005,128(4):2677-2687.
[8]  Jeschke MG,Finnerty CC,Kulp GA,et al.Combination of recombinant human growth hormone and propranolol decreases hypermetabolism and inflammation in severely burned children[J].Pediatr Crit Care Med,2008,9(2):209-216.
[9]  Jeschke MG,Kulp GA,Kraft R,et al.Intensive insulin therapy in severely burned pediatric patients:a prospective randomized trial[J].Am J Respir Crit Care Med,2010,182(3):351-359.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133