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围手术期多模式复合镇痛对膝关节置换患者血流变及粘附因子水平的影响

, PP. 901-903

Keywords: 多模式复合镇痛,血流变,粘附因子,膝关节置换

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Abstract:

目的探讨围手术期多模式复合镇痛对膝关节置换患者血流变及粘附因子水平的影响。方法选择接受膝关节置换的患者81例,随机分为对照组及观察组,对照组仅接受常规硬膜外麻醉,观察组在此基础上接受多模式复合镇痛,观察深静脉血栓(DVT)及术前、术后的视觉模拟评分(VAS)、血流变指标、细胞间黏附分子-1(ICAM-1)、血管细胞粘附因子-1(VCAM-1)的变化。结果观察组接受多模式复合镇痛后DVT发生6例,观察组3例,观察组DVT发生率低于对照组(P0.05);对照组术后ICAM-1、VCAM-1水平比观察组高(P<0.05)。结论围手术期多模式复合镇痛有助于缓解膝关节置换患者术后疼痛和改善血流变及粘附因子水平。

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