全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

睾丸原发性神经内分泌肿瘤临床与病理分析

Keywords: 睾丸,神经内分泌肿瘤,病理

Full-Text   Cite this paper   Add to My Lib

Abstract:

目的探讨睾丸原发性神经内分泌肿瘤(TNEN)的临床及病理组织学特征。方法对8例TNEN的临床表现、组织学形态、免疫表型及预后进行分析。结果我院共发现8例TNEN,占睾丸肿瘤的1.67%(8/479)。患者发病年龄18~65岁(平均38.5岁),均发生于单侧睾丸,左侧5例,右侧3例。阴囊彩超多普勒显示睾丸内可见低回声实性团块,肿块内可见丰富血流信号。根据美国癌症联合会(AJCC)标准,8例患者均属于IA期,并均实施睾丸根治切除术。术后病理提示6例为低级别TNEN,2例为中级别TNEN。8例免疫组化NSE、Synaptophysin、ChromograninA、CK-P均为阳性,而AFP、PLAP、α-inhibin和CD117均为阴性。结论TNEN临床表现无特异性,诊断主要依靠镜下肿瘤细胞的特点和免疫组化特征。

References

[1]  Wang WP. Primary carcinoid tumors of the testis:a clinicopathologic study of 29 cases[J]. Am J Surg Pathol,2010,34,519-524.
[2]  Zavala-Pompa A. Primary carcinoid tumor of testis. Immunohistochemical,ultrastructural,and DNA flow cytometric study of three cases with a review of the literature[J]. Cancer,1993,72:1726-1732.
[3]  Sasaki M. Primary carcinoid tumor of the testis metastatic to the para-aortic lymph nodes in six years after the first operation:a case report[J]. Hinyokika Kiyo,2009,55,233-236.
[4]  Pectasides D,Glotsos J,Bountouroglou NG,et al. Primary carcinoid of the testis with metastases. Case report and review of the literature[J]. J Buon,2002(7):153-156.
[5]  Mai KT,Park PC,Yazdi HM,et al. Leydig cell origin of testicular carcinoid tumour:immunohistochemical and electron microscopic evidence[J]. Histopathology,2006,49,548-549.
[6]  Merino J. Pure testicular carcinoid associated with intratubular germ cell neoplasia[J]. J Clin Pathol,2005,58,1331-1333.
[7]  CSCO神经内分泌肿瘤专家委员会.中国胃肠胰神经内分泌肿瘤专家共识[J].临床肿瘤学杂志,2013,18(9):815-832.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133