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来氟米特联合柳氮磺吡啶治疗强直性脊柱炎的临床观察

, PP. 201-203

Keywords: 来氟米特,柳氮磺吡啶,强直性脊柱

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Abstract:

目的探讨来氟米特联合柳氮磺吡啶治疗强直性脊柱炎的临床价值。方法选取2011年11月至2013年5月我院收治的122名强直性脊柱炎患者,随机分为治疗组和对照组两组,每组各61例,对照组采用柳氮磺吡啶治疗,治疗组在此基础上加用来氟米特治疗。对其临床疗效及晨僵、关节疼痛数量、扩胸试验、红细胞沉降率及C反应蛋白等指标的改善情况进行评定。结果治疗组的总有效率为93.44%,显著高于对照组的78.69%(P0.05),治疗6个月后治疗组晨僵、关节疼痛数量、扩胸试验、红细胞沉降率及C反应蛋白等指标均显著优于对照组,其中,以红细胞沉降率的组间差异最为明显(P<0.05)。结论柳氮磺吡啶与来氟米特相结合治疗强直性脊柱炎疗效明确,能够有效地缓解病情,阻断其进一步的发展。

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