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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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TLR4在肝癌患者外周血单核细胞中的表达及意义
, PP. 161-163
Keywords: 肝癌,TLR4,NF-κB,IL-6
Abstract:
目的研究肝癌患者外周血单核细胞TLR4的表达情况及意义。方法采用流式细胞术检测50例肝癌患者和30例健康正常人外周血单核细胞表面TLR4的表达,采用ELISA法检测肝癌组及对照组血浆NF-κB、IL-6的表达。结果肝癌患者外周血TLR4、NF-κB、IL-6表达明显高于正常对照组(P<0.01);肝癌患者TLR4的表达与NF-κB呈正相关(r=0.352,P<0.05);结论肝癌患者外周血TLR4表达较正常人明显增高,TLR4可能与原发性肝癌的发生密切相关。
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