Pilcher B,Dumin J,Sudbeck BD.The activity of collagenase-1 is required fo r keratinocyte migration on a typeⅠcollagen matrix[J].J Cell Biol,1997,137:1 445-1457.
[2]
Bellon G,Martiny L,Robinet A.Matrix metalloproteinases and matrikines in angiogenesis [J].Crit Rev Oncol Hematol,2004,49(3):203-220.
[3]
Tang Y,Nakada MT,Kesavan P.Extracellular matrix metalloproteinase indu cer stimulates tumor angiogenesis by elevating vascular endothelial cell growth fac tor and matrix metalloproteinases[J]. Cancer Res,2005,65(8):3193-3199.
[4]
Iwasaki H,Inoue H,Mituke Y.Doxycycline induces apoptosis by way of ca spa se-3 activitionn with inhibition of matrix metalloproteinase in human T-lymphob lastic leukemia CCRF-CEM cells [J]. J Lab Clin Med,2002,140:382-386.
[5]
Onoda T,Ono T,Dhar DK.Doxycycline inhibits cell proliferation and inv asive potential:combination therapy with cyclooxygenase-2 inhibitor in human colorectal cancer c ells[J].J Lab Clin Med,2004,143:207-216.
[6]
Salvi GE,Lang NP.Host response modulation in the management of periodo ntal disease[J]. J Clin Periodontal,2005,32(Suppl 6):108-129.
[7]
Bemward P,Wulf S,Rita S,et al.Overexpression of matrix metalloprotei nas e-2 predicts unfavorable outcome in early-stage non-small cell lung cancer[ J]. Clinical Cancer Research,2000,6:3944-3948.
[8]
Thomas P,Khokka R,Shepherd FA,et al.Differential expression of matri x m etalloproteinases anf their inhibitors in non-small cell lung cancer[J]. Path ol,2000,190(2):150-156.
[9]
Gonzalez AG,Iturrea C,Vadillo F,et al.72ku(MMP2)and 92ku(MMP9)type I V c ollagenase production and activity in different histologic types of lung cancer [J]. Pathobiology,1998,66 (1):5-15.
[10]
Axisa B,Nalor AR,BeII PR,et al.SimpIe and reliabIe method of do xycyc line determination in human plasma and biological tissues[J]. Chromatogr B,2 000,744(2):359.
[11]
Curran S,Murray GI.Matrix metalloproteinases in tumor invasion an d metastasis[J].J Pathol,1999,189:300-308.
[12]
Deryugina EI,Borudon MA,Jungwirth K.Functional activation of intergri n a lpha V beta 3 in tumor cells expressing memberane-typeⅠMatrix metalloproteinase [J]. Int J Cancer,2000, 86:15- 23.
[13]
Fang J,Shing Y,Wiederschain D.Matrix metalloproteinase-2 is r equired for the switch to the angiogenic phenotype in a tumor model[J]. Proc Natl Acad S ci USA,2000,97(8):3884-3889.
[14]
Jumper C,Cobos E,Lox C.Determination of the serum matrix meta lloprotei- 9(MMP-9)and tissue inhibitor of matrix metalloproteinase-1(TIMP-1)in patient s with either advanced small-cell lung cancer or non-smal-cell lung cancer prior to treatment[J]. Respir Med,2004,98(2):173-177.
[15]
Hofmann UB,Eggert AA,Blass K.Expression of matrix metalloproteinases in the micro- environment of spontaneous and experimental melanoma metastases reflects the req uirements for tumor formation[J]. Cancer Res,2003,63(23):8221-8225.
[16]
Cheung PY,Sawick G,Wozniak M.Matrix metalloproteinases-2 contribut es to ischemia- Reperfusion injury in the heart[J].Circulation,2000,101(15):1833-1 839.
[17]
Cakir Y,Hahn KA.Direct action by Doxycycline against canin eosteosarc oma cell proliferation and collagenase(MMP-1)activity in vitro[J].In Vivo,1999,13 (4):327-331.
