Hoffmann C, Finsel I, Hilbi H. Purification of Pathogen Vacuoles from Legionella-infected Phagocytes[J]. J Vis Exp,2012,64: 3791-4118.
[2]
Urwyler S, E Brombacher, H Hilbi.Endosomal and secretory markers of the Legionella-containing vacuole[J].Commun Integr Biol,2009,2:107？109.
[3]
Urwyler S, Y Nyfeler, C Ragaz, et al. Proteome analysis of Legionella vacuoles purified by magnetic immunoseparation reveals secretory and endosomal GTPases[J]. Traffic,2009,10:76？87.
[4]
Bruggemann H, A Hagman, M Jules, et al.Virulence strategies for infecting phagocytes deducedfrom the in vivo transcriptional program of Legionella pneumophila [J]. Cell Microbiol,2006,8:1228-1240.
[5]
Tsuyoshi Hayashi, Masahiro Nakamichi, Hirotaka Naitou, et al.Proteomic Analysis of Growth Phase-Dependent Expression of Legionella pneumophila Proteins Which Involves Regulation of Bacterial Virulence Traits[J]. PLoS One, 2010,5:e11718.
[6]
Palusi？ska-Szysz M, Russa R,et al.Chemical structure and biological significance of lipopolysaccharide from Legionella[J]. Recent Pat Antiinfect Drug Discov,2009,4:96-107.
[7]
M Palusinska-saysz, M Janczarek.Innate Immunity to Legionella and Toll-like Receptors [J].Folia Microbiol,2010,55:508？514.
[8]
Newton HJ, Ang DK, van Driel IR,et al. Molecular pathogenesis of infections caused by Legionella pneumophila[J].Clin Microbiol Rev, 2010,4(23):274-298.
[9]
Juli C, Sippel M, J？ger J,et al. Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein[J]. J Med Chem, 2011,54:277-83.
[10]
Emmy De Buck, Jozef Anne,Elke Lammertyn.The role of protein secretion systems in the virulence of the intracellular pathogen Legionella pneumophila[J]. Microbiology,2007, 153: 3948？3953.
[11]
Gerlach RG,Hensel, M. Protein secretion systems and adhesins: the molecular armory of Gram-negative pathogens[J]. Med Microbiol,2007,297:401？415.
[12]
Cianciotto NP.Many substrates and functions of type II secretion: lessons learned from Legionella pneumophila[J]. Future Microbiol, 2009,4(7):797-805.
[13]
Pearce MM,NP Cianciotto. Legionella pneumophila secretes an endoglucanase that belongs to the family-5 of glycosyl hydrolases and is dependent upon type II secretion [J]. FEMS Microbiol Lett, 2009,300:256-264.
[14]
Rossier O, J Dao, et al.Cianciotto. The type II secretion system of Legionella pneumophila elaborates two aminopeptidases, as well as a metalloprotease that contributes to differential infection among protozoan hosts[J]. Appl Environ Microbiol, 2008,74:753？761.
[15]
DebRoy S,J Dao, M Soderberg, et al. Legionella pneumophila type II secretome reveals unique exoproteins and a chitinase that promotes bacterial persistence in the lung[J]. Proc Natl Acad Sci USA,2006,103:19146？19151.
[16]
Rossier O, J Dao, NP Cianciotto. A type II secreted RNase of Legionella pneumophila facilitates optimal intracellular infection of Hartmannella vermiformis[J]. Microbiology,2009,155:882？890.
[17]
Steinert M, Heuner K, Buchrieser C.Albert-Weissenberger. Legionella pathogenicity: genome structure,regulatory networks and the host cell response[J]. Med Microbiol,2007, 297:577？587.
Albert-Weissenberger C, Cazalet C, Buchrieser C.Legionella pneumophila ？ a human pathogen that co-evolved with fresh water protozoa[J]. Cell Mol Life Sci,2007,64:432-448.
[20]
Marta Palusi？ska-Szysz1,Monika Cendrowska-Pinkosz.Occurrence and pathogenicityof the family of Legionellaceae[J]. Postepy Hig Med Dosw,2008, 62:337-353.
[21]
Shin S.Innate Immunity to Intracellular Pathogens: Lessons Learned from Legionella pneumophila[J].Adv Appl Microbiol, 2012,79:43-71.
[22]
Schuelein R, Ang DK, van Driel IR,et al. Immune Control of Legionella Infection: An in vivo Perspective[J]. Front Microbiol,2011,2:126.
[23]
Joshi AD, Swanson MS.Secrets of a Successful Pathogen: Legionella Resistance to Progression Along the Autophagic Pathway[J].Front Microbiol, 2011,2: 138.
[24]
Albert-Weissenberger C, Sahr T, Sismeiro O,et al.Control of Flagellar Gene Regulation in Legionella pneumophila and Its Relation to Growth Phase[J]. J Bacteriol,2010,192(2):446-55.
[25]
Shevchuk O, J？ger J, Steinert M.Virulence properties of the legionella pneumophila cell envelope[J]. Front Microbiol, 2011,2:74.
[26]
Andreas Ceymann,Martin Horstmann,Philipp Ehses,et al.Solution structure of the Legionella pneumophila Mip-rapamycin complex[J].BMC Structural Biology,2008, 8:1-12.
[27]
Wagner C,Khan AS,Kamphausen T,et al.Collagen binding protein Mip enables Legionella pneumophila to transmigrate through a barrier of NCI-H292 lung epithelial cells and extracellar matrix[J].Cell Microbiology,2007, 9: 450-462.
