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指长比与PCOS及其并发症的相关性研究

, PP. 438-443

Keywords: 指长比,多囊卵巢综合征,代谢特征,临床特征

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Abstract:

目的探讨指长比与多囊卵巢综合征(PCOS)及其临床、代谢特征的关系。方法采用电子游标卡尺测量192例以2003年标准诊断的PCOS组患者及同期就诊的110例卵巢功能正常非PCOS(对照组)患者左、右手各指长,比较PCOS组与对照组,PCOS临床、代谢特征不同组间左、右手各指长比(2DDK∶3D、2DDK∶4D、2DDK∶5D、3DDK∶4D、3DDK∶5D、4DDK∶5D)的差异。结果PCOS与对照组双手指长比均呈2DDK∶3D<2DDK∶4D<3DDK∶4D<2DDK∶5D<4DDK∶5D<3DDK∶5D趋势,右手各指长比高于左手各相应指长比;各指长比左右手两组差值比较有统计学意义(?t?=?2.21、3.37、4.57、2.92、4.46、3.45,?P?<0.01)。与对照组比较,PCOS组左手2DDK∶4D显著低于对照组(?t?=2?26,?P?<0.05);左手2DDK∶5D、3DDK∶4D、右手2DDK∶5D、3DDK∶4D、3DDK∶5D、4DDK∶5D显著高于对照组(?t?=2.22、1?98、-2.87、?-2.55、-2.31,?P?<0.05,?P?<0.05);右手2DDK∶4D高低分布不同PCOS高2DDK∶4D者多,对照组低2DDK∶4D多(χ2=12.14,?P?<0.01)。PCOS患者中,有PCO组左手3DDK∶4D显著低于无PCO组(?t?=2.47,?P?<0?05);双侧PCO组左手3DDK∶4D、3DDK∶5D、右手3DDK∶5D、4DDK∶5D均呈低于非双侧PCO组趋势,但组间左手3DDK∶4D、右手、4DDK∶5D差异有统计学意义(?t?=2.12、2.07,?P?<0.05),LH/FSH倒置组左手2DDK∶3D、2DDK∶4D低于无倒置组(?t?=2.12,2.39,?P?<0.05);有胰岛素抵抗(IR)组左、右手3DDK∶4D、2DDK∶4D、右手2DDK∶4D高于无IR组,但组间仅右手3DDK∶4D差异有统计学意义(?t?=-2.04,?P?<0.05);左手3DDK∶4D高空腹血糖组显著低于血糖正常组(?t?=?2.87,?P?<?0.01)。结论本地区不孕群体PCOS患者指长比左手2DDK∶4D低、右手高指长比及其右手2DDK∶4D分布特征不同与其他群体,指长比与PCOS及其部分临床、代谢特征有关。

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