[ Collins F, Galas D. A new five-year plan for U. S Human Genome pr oject 1998- 2003[ J] . Science, 1998,282: 682～698
[6]
[ Fields C, Adams D. How many genes in the human genome[ J] . Natur e Genetics, 1994, 7: 345
[7]
[ Hieter P Bo guski M. Functional genomics: it’s all how y ou r ead it [ J] . Science, 1997, 278( 5338) : 601～602
[8]
[ Miklos G L, Rubin G M. T he role o f the genome pr oject in determining gene function: insig hts fr om model or ganisms[ J] . Cell, 1996, 86( 4) : 521～529
[9]
[ Pennisi E. NRC Oks long-delay ed sur vey of human genome div ersity[ J] . Science, 1997, 278( 5338) : 568
[10]
[ Row en L, Mahairas G, Hoo d L. Sequence of the human g enome[ J] . Science, 1997, 278( 5338) : 605～607
[11]
[ Schuler G D. A g ene map o f the human genome[ J] . Science, 1996, 274( 5287) : 540～546
[12]
[ Weber J L, Myer s E W. Human w ho le-g enome sho tgun sequencing[ J] . Genom e Res, 1997, 7: 401～409
[13]
[ Bar bujani. Appo rtionment of human DNA diver sity [ J] . Pr oc Natl Acad Sci 1997, 94: 4516
[14]
[ O Brien, S J. T he promise of compar ative g enomics in mammals[ J] . Science, 1999, 286: 458～481
[15]
[ Dean M . Polymor phism Admix ture T yping in Human Et hnic population[ J] . Am J Hum Gent , 1994, 55( 4) :788～808
[16]
[ Corder E H. Gene dose of apolipoprotein E type 4 allele and the r isk of Alzheimer’s disease in late onset families Science[ J] . 1993, 261( 5123) : 921～923
[17]
[ Ho usman D Ledley F D.Why a pharm acog enomics? Why now [ J] . Nat Biotechnolog y, 1998, 16: 492～493
[18]
[ Marshall A. Genset-Abbett deal her alds pharmacog enomics era [ J] . Nat Biotechnolog y, 1997, 15: 829～830
[19]
[ Patr ick W. Genetic v ariation as a Guide to Druag Dev elopment[ J] . Science, 1998, 281: 1820～1821
[20]
[ Brenner S. Characterizatio n of the pufferfish( Fug u) genome as a compact m odel ver tebrate genome [ J] .Natur e, 1993, 366( 6452) : 265～268
[21]
[ Bult C T . Complete g enome sequence of the methanog enic archaeo n, Methano coccus jannaschii[ J] . Science,1998, 273( 5278) : 1058～1073
[22]
[ Copeland N G. A genetic linkag e map of the mouse: current application and futur e pr ospects[ J] . Science,1993. 262( 5130) : 57～66
[23]
[ DeBr y R W. Human/ mouse homology relationships[ J] . Genomics, 1996, 33( 3) : 337～351
[24]
[ Ecker V R. Genome sequencing , Genes blosson from a weed[ J] . Nature, 1998 , 39( 6666) : 438～439
[25]
[ Huy nen M A. Different ial g enome display [ J] . Trends Genet, 1997, 13( 10) : 389～390
[26]
[ Judson H F. The Eig hth Day of Cr eat ion: M aker s o f the Rev elution in Biolo gy [ M ] . 1998, Ex pandel Edition. New York cold Spr ing Harbor Laborato ry press.
[27]
[ Kappes S M . A second-gener ation linkag e m ap of the bo vine genome[ J] . Genome Res, 1997, 7( 3) : 235～249
[28]
[ Konin E V. Prokar yotic genomics: the emerg ing parodigm of g enome-based microbiology [ J] . Curr Opin Genet Dev, 1997, 7( 6) : 757～763
[29]
[ Ly ons L A. Compar ative ancho r tag ged sequences for integ rativ e mapping of mammalian genomes[ J] .Natur e Genet, 1997, 15( 1) : 47～56
[30]
[ McQueen H A. CpG islands of chicken one concer trated on microchromo somes [ J] . Nat Genet, 1996, 12( 3) : 321～324
[31]
[ Mckusick V. Genomics: structur al and functional studies of genomes[ J] . Genomics, 1997, 45( 2) : 244～249
[32]
[ Pennisi E. Genomics data shake tree of life[ J] . Science, 1998, 280( 5364) : 672～674
[33]
[ E S For ce A. Ver tebr ate g enome evolutio n and the Zebrafish g ene map[ J] . Nat Genet, 1998, 18( 4) : 345～349
[34]
[ Sasaki T . He Japanese r ice g enome r esearch pr ogr am[ J] . Genome Res, 1996, 6( 8) : 661～666
