临床药师对中药注射剂使用的干预作用分析

【】　目的　验证临床药师对我院中药注射剂合理使用进行干预的效果。　方法　对比分析2010年临床药师干预前后中药注射剂的合理使用情况，随机抽取2010年1-6月合格病历1000份，设为非干预组；随机抽取2010年9月-2011年2月合格病历1000份，设为干预组；评估临床药师的干预作用。　结果　非干预组中药注射剂的使用率为31.10%，干预组为19.00%，差异有统计学意义（χ2=38.991，P=0.000）；非干预组适应证不合理的为6.00%，干预组为2.10%，差异有统计学意义（χ2=19.570，P=0.000）；非干预组发生不良反应15例，干预组发生3例，两组不良反应发生率差异有统计学意义（χ2=8.073，P=0.004）；中药注射剂的用法用量趋于规范。　结论　临床药师对中药注射剂临床使用的干预行之有效，对促进医院安全、有效、合理使用中药注射剂起到了积极作用。【Abstract】　Objective　Toexploretheeffectsofclinicalpharmacistsinterventionontraditionalchinesemedicineinjection.　Methods　ComparedtherationalusageoftraditionalChinesemedicineinjectionin2010aftertheinterventionofclinicalpharmacists.Atotalof1000clinicalcaserecordsfromJanuarytoJune2010wererandomlyselectedandwasnamedasthenon-interventiongroup;another1000clinicalcaserecordsfromSeptember2010toFebruary2011wererandomlyselectedandwasnamedastheinterventiongroup.Theeffectoftheclinicalpharmacistswereevaluated.　Results　TheutilizationrateoftheChinesemedicineinjectionwas31.10%innon-interventiongroupand19.00%intheinterventiongroupwithasignificantdifferencebetweenthetwogroups(χ2=38.991，P=0.000).Theirrationalityofindicationwas6.00%innon-interventiongroupand2.10intheinterventiongroupwithasignificantdifferencebetweenthetwogroups（χ2=19.570，P=0.000）.Theadversereactionwasfoundin15patientsinnon-interventiongroupandinthreepatientsintheinterventiongroupwithasignificantdifferencebetweenthetwogroups（χ2=8.073，P=0.004）.TheusageanddosageofChinesetraditionalmedicineinjectionwastendtobenormative.　Conclusion　TheinterventionontraditionalChinesemedicineinjectionbyclinicalpharmacistsiseffective,whichisaimportantpartinpromotingtherationaluseoftraditionalChinesemedicineinjection.