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华西医学  2011 

老年血清胱抑素C水平与急性心肌梗死相关性研究

, PP. 1309-1311

Keywords: 胱抑素C,急性心肌梗死,老年

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Abstract:

【】 目的 观察70岁以上老年心肌梗死急性期血清胱抑素C(cystatinC,CysC)水平,探讨急性心肌梗死后CysC水平变化的意义。 方法 顺序入选2010年7月-2011年7月期间70岁以上急性心肌梗死患者58例及正常对照58例。入选对象均经冠状动脉造影检查确诊或排除诊断,记录急性心肌梗死患者梗死部位和梗死相关血管,并计算Gensini积分。所有入选对象采血,使用乳胶增强免疫透射比浊法测定急性期血清CysC水平。 结果 心肌梗死急性期,血清CysC水平低于正常对照组(P<0.05);不同冠状动脉病变评分与血清CysC水平呈负相关,Gensini积分越高,血清CysC水平越低。 结论 血清CysC与冠心病关系密切。检测CysC,为冠心病的风险预测、老年患者危险分层和治疗提供一条新的线索和途径。

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