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华西医学  2014 

抗磷脂综合征临床特征分析

DOI: 10.7507/1002-0179.20140185, PP. 612-615

Keywords: 抗磷脂综合征,血栓形成,抗磷脂抗体

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Abstract:

目的 探讨抗磷脂综合征(APS)的临床特征和实验室检查特点。方法 回顾性分析总结2009年1月-2012年1月26例APS患者的临床表现和实验室检查。结果 患者共26例,男8例,女18例。原发性APS7例,继发性APS19例,其中继发系统性红斑狼疮11例。21例血栓形成患者中静脉血栓16例,动脉闭塞7例,其中静脉血栓和动脉闭塞同时存在2例。血栓事件以下肢深静脉血栓、脑梗死为常见。在16例已婚女性中7例出现病态妊娠,4例为习惯性自发性流产。57.7%患者出现血小板下降,69.2%患者不同程度血红蛋白下降。结论 APS以血栓形成及病态妊娠为特点。其临床表现具有多样性。早期诊治是改善预后的关键。

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