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华西医学  2014 

慢性乙型肝炎核苷类似物抗病毒治疗应答的影响因素

DOI: 10.7507/1002-0179.20140236, PP. 776-779

Keywords: 慢性乙型肝炎,核苷类似物,抗病毒治疗,影响因素

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Abstract:

我国乙型肝炎病毒感染率高,慢性乙型肝炎的治疗目标是最大限度地长期抑制乙型肝炎病毒,延缓和减少疾病进展及肝脏失代偿、肝硬化、肝细胞癌等的发生,从而改善生活质量和延长存活时间。随着干扰素及核苷类似物两大类抗病毒治疗的进展,发现不同的患者在治疗疗效上有很大差异,研究认为,核苷类似物抗乙型肝炎病毒治疗的疗效主要受药物、病毒及宿主3个方面因素的影响。

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