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华西医学  2014 

结核感染T细胞斑点试验在血液病合并结核中的诊断价值

DOI: 10.7507/1002-0179.20140183, PP. 607-610

Keywords: 结核感染T细胞斑点试验,血液病,结核病,诊断价值

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Abstract:

目的 评价结核感染T细胞斑点试验(T-SPOT.TB)在血液病合并结核感染患者中的诊断价值。方法 应用T-SPOT.TB对2012年3月-2013年4月间收治的82例结核感染待排的血液病患者外周血标本进行检测。结果 T-SPOT.TB检测对于血液病患者合并结核感染的阳性检出率为59.09%(13/22),明显高于结核抗体检测的13.64%(3/22),P<0.05。T-SPOT.TB检测血液病患者合并结核感染的灵敏度和特异度分别为59.09%(13/22)、68.33%(41/60),灵敏度优于结核抗体检测(P<0.05)。结论 T-SPOT.TB检测对于血液病患者合并结核感染具有较大的辅助诊断价值,对于确诊结核感染阳性患者的诊断价值大于确诊结核感染阴性患者的诊断价值,临床上可作为血液病患者合并菌阴结核感染的辅助诊断。

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