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华西医学  2011 

罗哌卡因切口预注射联合曲马多对腹腔镜下胆囊切除术后疼痛的影响

, PP. 1864-1867

Keywords: 罗哌卡因,曲马多,腹腔镜胆囊切除术,疼痛

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Abstract:

【】 目的 评估罗哌卡因切口预注射联合曲马多对腹腔镜下胆囊切除术(laparoscopiccholecystectomy,LC)术后疼痛的影响。 方法 选取2010年6月-2011年4月行择期LC患者120例,年龄18~65岁,美国麻醉师协会Ⅰ~Ⅱ级,采用完全随机的设计分组0.75%罗哌卡因10mL切口注射+术毕静脉注射曲马多(2mg/kg)组(A组,n=30);生理盐水10mL切口注射+术毕静脉注射曲马多(2mg/kg)组(B组,n=30);0.75%罗哌卡因10mL切口注射+术毕静脉注射生理盐水10mL组(C组,n=30);生理盐水组(D组,n=30)。术后2、4、6、12、24h分别评估右上腹部、右肩背部和腹壁切口疼痛进行视觉模拟评分(visualanalogscale,VAS)。 结果 右上腹部及右肩背部疼痛VAS比较与D组相比,A、B组VAS评分明显减少(P0.05);B组与A组相比,2~24hVAS评分明显增加(P0.05).GroupAhadsignificantlylowerpainscoresthangroupB(P<0.05)andC(P<0.01)atpostoperativehours2,4,6,12,and24.AbdominalincisionpainVAScomparisonVASscoresweresignificantlyloweringroupA,BandCthaningroupD(P<0.05).GroupAhadsignificantlylowerpainscoresthangroupB(P<0.05)andC(P<0.01)atpostoperativehours2,4,6,12,and24. Conclusion PreincisionalropivacaineatthebeginningofLCcombinedwithtramadolintravenousinjectionattheendcaneffectivelyalleviatepostoperativepainafterlaparoscopiccholecystectomy.

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