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华西医学  2011 

外周血粒细胞缺乏症感染实验室诊断的进展

, PP. 1810-1813

Keywords: 粒细胞缺乏症,降钙素原,白介素-6,内毒素

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Abstract:

【】 恶性血液病患者强烈化疗诱导的粒细胞缺乏症常并发感染,且病死率高。快速而准确地进行病原学诊断,尽早使用抗生素为治疗争取时间,可大大降低感染病死率。而临床常用感染的实验室诊断指标均有其局限性,不能满足临床需要。目前国内外多项研究提示降钙素原、白介素-6、内毒素有助于粒细胞缺乏症伴感染的诊断及治疗。现就降钙素原、白介素-6、内毒素的来源、生物学活性及在临床中的应用做一综述。

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