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华西医学  2015 

病毒相关性弥漫大B细胞淋巴瘤的临床及免疫学特点

DOI: 10.7507/1002-0179.20150164, PP. 569-572

Keywords: 淋巴瘤,非霍奇金淋巴瘤,弥漫性大B细胞淋巴瘤,病毒感染,免疫亚型

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Abstract:

弥漫性大B细胞淋巴瘤(DLBCL)作为非霍奇金淋巴瘤(NHL)中最常见的一种亚型,在过去的10年里,其发病率明显增加,越来越成为人们关注的重点。作为一组在形态学、生物学行为和临床上具有显著异质性的恶性肿瘤,DLBCL的病因学及发病机制复杂。多年来,病毒感染与DLBCL的关系一直成为人们关注的焦点之一。现主要讨论Epstein-Barr病毒、人类获得性免疫缺陷病毒、乙型肝炎病毒、丙型肝炎病毒及人类T淋巴细胞/白血病病毒1型-1感染相关性DLBCL的临床及免疫学特点。

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