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华西医学  2015 

70 kV颅脑CT灌注成像的可行性研究

DOI: 10.7507/1002-0179.20150546, PP. 1910-1913

Keywords: 颅脑,体层摄影术,X线计算机,灌注,辐射剂量

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Abstract:

目的?探讨70kV管电压技术对颅脑CT灌注参数及图像质量的可行性。方法?2013年10月-2014年2月拟行CT灌注检查的患者,按检查时间分为A、B两组。所有的患者采用西门子128层双源CT进行扫描。分别从每组中筛选出15例经CT检查无颅脑疾病患者的图像数据进行研究。在A、B两组患者的额叶室旁、尾状核、壳、丘脑、颞枕叶放置面积为80mm2的感兴趣区进行测量,分别测量感兴趣区内脑血流量、脑血容量、平均通过时间。比较两组图像丘脑和额叶室旁脑白质的对比噪声比、信噪比。请2位高年资神经影像学诊断医生对两组患者的图像进行主观评分(5分=最好,1分=最差)。记录CT剂量指数、CT剂量长度乘积,计算出有效剂量来评价两组患者的辐射剂量。统计学方法采用独立样本t检验。结果?两组患者感兴趣区内的灌注参数值差异无统计学意义(P>0.05)。两组患者图像质量主观评分和客观评价差异均无统计学意义(P>0.05)。B组患者的CT剂量指数、CT剂量长度乘积、有效剂量较A组患者均降低了35%。结论?使用西门子第2代双源CT最新70kV管电压技术行颅脑CT灌注检查,对颅脑灌注参数值和图像质量无明显影响,而且辐射剂量明显降低。

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